Coronavirus (OLD)

[jfman]

Originally Posted by tweetiepooh

And what happens if we get COVID-20/21/22/23/30? Are they going to be like the cold so keep returning and reinfecting?

It's highly unlikely, however we should be prepared. Have PPE available and a mechanism to quickly scale up testing. Intervene early, screen people at airports and isolate them as appropriate and contact trace. It's not rocket science and while moderately expensive by 2019 terms it's a relative bargain compared to a 35% drop in forecast GDP.

[tweetiepooh]

Originally Posted by jfman

It's highly unlikely, however we should be prepared. Have PPE available and a mechanism to quickly scale up testing. Intervene early, screen people at airports and isolate them as appropriate and contact trace. It's not rocket science and while moderately expensive by 2019 terms it's a relative bargain compared to a 35% drop in forecast GDP.

That is all true, herd immunity to a changing target is not likely. I think we also need to work globally and share more both is resource and information. If we can shut down infection closer to source before it spreads that becomes much easier to manage and is likely to be cheaper in the long run. That would mean maybe producing equipment that is portable so if infection starts in 3rd world it can be used there.

[denphone]

Hopefully consumers should find it a little bit easier to get hold of paracetemol after this deal.

https://www.gov.uk/government/news/u...of-paracetamol

[Hom3r]

On a very positive side


A 99 year old Captain Tom Moore wanted to raise £1,000 for the NHS buy walkiing 100 lengths of his garden.

Well as of 12:58pm on the 15th of April.

It's at £6,305,649.00.

The Just Giving site is struggling to refresh, at one poit 90,000 people were donating at the same time.

https://www.justgiving.com/fundraisi...swalkforthenhs


A Pride of Britain award bekons

What we need is rain and lots of it..That would keep more people indoors.

[Sephiroth]

Originally Posted by mrmistoffelees

The herd immunity that we don’t know will work ?
<SNIP>

You are right, of course - but then the vaccine when it comes may also not work for the same reason unless they've found a clever killer add-in.

---------- Post added at 13:53 ---------- Previous post was at 13:51 ----------

Originally Posted by Hom3r

On a very positive side


A 99 year old Captain Tom Moore wanted to raise £1,000 for the NHS buy walkiing 100 lengths of his garden.

Well as of 12:58pm on the 15th of April.

It's at £6,305,649.00.

The Just Giving site is struggling to refresh, at one poit 90,000 people were donating at the same time.

https://www.justgiving.com/fundraisi...swalkforthenhs


A Pride of Britain award bekons

... in addition to the Queen's telegram. Another medal to add to his row.

Originally Posted by Maggy

What we need is rain and lots of it..That would keep more people indoors.

Not much fun queueing at the shops / supermarket / pharmacy though

[ianch99]

Originally Posted by pip08456

I think all of us echo what Chris has said.

Hear hear ..

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Originally Posted by jonbxx

It looks like the big boys, namely Glaxo Smithkline and Sanofi Pasteur are getting together to work on a vaccine - https://www.sanofi.com/en/media-room...04-14-13-00-00

These guys know their stuff and critically have the manufacturing scale at their plants in Belgium and France to get things done

If the vaccine is being manufactured in the EU, does that fact that we have left the EMA affect timely access to the vaccine?

[pip08456]

Originally Posted by ianch99

Hear hear ..

---------- Post added at 16:04 ---------- Previous post was at 15:53 ----------



If the vaccine is being manufactured in the EU, does that fact that we have left the EMA affect timely access to the vaccine?

As we are still in the transition we are still in the EMA.

[heero_yuy]

GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source

[jonbxx]

Originally Posted by heero_yuy

GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source

GSK doesn't really have vaccine manufacturing in the UK. The bulk of the local vaccine manufacturing is in Rixensart in Belgium. Blimmin huge site that too. However, it's not clear if the vaccine final formulation will be Sanofi, GSK or both.

(super geeky background, GSK is very good at whole viral vaccines, especially egg based products. Sanofi good at viral component vaccines)

On the regulation, the UK regulator (MHRA) is being super flexible on regulations so we would very likely take EMA approval directly even if approved after the end of the transition period. Where there's a will, there's a way...

[mrmistoffelees]

Originally Posted by Sephiroth

You are right, of course - but then the vaccine when it comes may also not work for the same reason unless they've found a clever killer add-in.

---------- Post added at 13:53 ---------- Previous post was at 13:51 ----------


... in addition to the Queen's telegram. Another medal to add to his row.

Hence clinical trials

[Pierre]

Originally Posted by jfman

It's highly unlikely,

Even though you are CableForums most eminent chief virologist, the correct answer I think would be, we don’t know.

Unless you’ve done the research, of course.

Have PPE available

Absolutely, I think a national store of PPE is required, depends on the shelf life as to how much we can stockpile.

a mechanism to quickly scale up testing

Yes a “mechanism” - don’t know what it is, but we should have it.

Intervene early, screen people at airports

Proven not to be effective during this pandemic.

https://www.eurosurveillance.org/con...0.25.5.2000080

Due to the duration of the incubation period of 2019-nCoV infection, we find that exit or entry screening at airports for initial symptoms, via thermal scanners or similar, is unlikely to prevent passage of infected travellers into new countries or regions where they may seed local transmission.

I’m going to downgrade you to “junior virologist” for this error.

isolate them as appropriate and contact trace.

isolate them based on airport screening that is too inaccurate?

It's not rocket science

it certainly isn’t, it’s infectious disease management, when you don’t know the disease and you don’t know how infectious it is, you don’t know the mortality rate, you don’t know how if affects each individual............in short you know sweet FA about anything and you have to make decisions everyday based on the data of the previous day.

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Originally Posted by Paul

Not much fun queueing at the shops / supermarket / pharmacy though

I find the whole thing very civilised. I appreciate it may vary depending where you are and whilst the weather is good.

But I happily queue for about 5-10mins to get into my local Tesco or CoOp and it’s all very chilled and relaxed.

Originally Posted by heero_yuy

GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source

Originally Posted by jonbxx

GSK doesn't really have vaccine manufacturing in the UK. The bulk of the local vaccine manufacturing is in Rixensart in Belgium. Blimmin huge site that too. However, it's not clear if the vaccine final formulation will be Sanofi, GSK or both.

(super geeky background, GSK is very good at whole viral vaccines, especially egg based products. Sanofi good at viral component vaccines)

On the regulation, the UK regulator (MHRA) is being super flexible on regulations so we would very likely take EMA approval directly even if approved after the end of the transition period. Where there's a will, there's a way...

Also the EU thing really won't matter here. There is a lot of money being thrown at this and as soon as a viable vaccine is found it'll be produced on a scale never seen before.

Originally Posted by Pierre

I find the whole thing very civilised. I appreciate it may vary depending where you are and whilst the weather is good.

But I happily queue for about 5-10mins to get into my local Tesco or CoOp and it’s all very chilled and relaxed.

You did note that was a reply to "lots of rain", right ?

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In other news, a 106 year old has recovered.

https://www.bbc.co.uk/news/uk-englan...ngham-52296196