20-12-2020, 17:18
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#1816
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cf.mega pornstar
Join Date: Jan 2006
Posts: 19,217
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Re: Coronavirus
Quote:
Originally Posted by Paul
Exactly how does it transmit more easily ?
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Spike protein according to the egg head on the radio yesterday, it's the way viruses hijack cells and apparently it's easier for the mutant. Tbh I'm just a simple guy, very simple some would say but isn't this the logical advancement, a virus that is easier to transmit but less deadly to the host?
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20-12-2020, 17:22
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#1817
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Woke and proud !
Join Date: Jun 2004
Services: TV, Phone, BB, a wife
Posts: 9,950
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Re: Coronavirus
Bad news for anyone planning to run abroad, we're not wanted.
Quote:
Countries across Europe have started banning Britons from travelling in a bid to halt the spread of the new variation of coronavirus.
The Netherlands was the first to do so, prohibiting those from the UK flying in, followed by Belgium, whose restrictions apply not only to planes but also those entering by car or train (including the Eurostar). Austria and the Czech Republic are the latest nations to take action, and Ireland, Germany and France are also considering which measures to implement.
Italy’s foreign minister Luigi Di Maio announced on Twitter: “As a government we have a duty to protect Italians, so for this reason, after warning the British government… we are about to sign the order to suspend flights with Great Britain.”
Outside of Europe, Israel has announced that anyone travelling from the UK must quarantine for two weeks in a designated hotel.
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https://www.telegraph.co.uk/news/202...holiday-plans/
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20-12-2020, 17:23
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#1818
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cf.mega poster
Join Date: Jul 2004
Location: Hiding . . from all the experts
Posts: 4,454
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Re: Coronavirus
Quote:
Originally Posted by Paul
Exactly how does it transmit more easily ?
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Very good question.
Somebody may be along soon to explain that a multitude of virologists, scientists and Government busybodies have found - after very extensive testing and data manipulation - that there are 0.0371% more of the virus in droplets expelled from the mouth when shouting in anger at next doors cat wandering through your flower beds.
__________________
“You get a wonderful view from the point of no return.” ~ T. Pratchett
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20-12-2020, 17:28
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#1819
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Perfect Soldier
Join Date: Mar 2009
Location: Worthing West Sussex
Age: 68
Services: VM 500M SH3 thingy
in modem mode
XL TV V6 Sony Bravia smart TV and M phone
Posts: 11,214
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Re: Coronavirus
Quote:
Originally Posted by Carth
shouting in anger at next doors cat wandering through your flower beds.
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Nerf gun. 
__________________
History is much like an endless waltz: The three beats of war, peace and revolution continue on forever.
However history will change with my coronation - Mariemaia Khushrenada
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20-12-2020, 17:34
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#1820
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laeva recumbens anguis
Cable Forum Team
Join Date: Jun 2006
Age: 68
Services: Premiere Collection
Posts: 43,792
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Re: Coronavirus
Quote:
Originally Posted by Sephiroth
So is it migrants arriving in Kent?
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If you mean the variant, there is no evidence of that, no matter how many times the Telegraph tries to dog-whistle that message...
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20-12-2020, 17:38
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#1821
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Trollsplatter
Join Date: Jun 2003
Location: North of Watford
Services: Humane elimination of all common Internet pests
Posts: 38,220
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Re: Coronavirus
Quote:
Originally Posted by TheDaddy
Spike protein according to the egg head on the radio yesterday, it's the way viruses hijack cells and apparently it's easier for the mutant. Tbh I'm just a simple guy, very simple some would say but isn't this the logical advancement, a virus that is easier to transmit but less deadly to the host?
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The spike protein is the virus' skeleton key - it 'unlocks' the target cell so the virus can get inside. Once inside it can set about turning the cell into a virus factory. The new variant virus has a more efficient design of spike protein that is more effective at unlocking target cells in the human body.
In a sense the most evolved virus would happily reside in a host body without damaging it or worse, killing it, but as a virus damages a host in the very act of turning host cells into virus factories in reality what it really needs is to be highly contagious, but not rapidly fatal. As long as it can spread to as many other people as possible without killing its host or incapacitating the host so the host doesn't come into contact with other potential hosts, the virus could be said to be doing very well.
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20-12-2020, 17:44
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#1822
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laeva recumbens anguis
Cable Forum Team
Join Date: Jun 2006
Age: 68
Services: Premiere Collection
Posts: 43,792
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Re: Coronavirus
Quote:
Originally Posted by Paul
Exactly how does it transmit more easily ?
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https://virological.org/t/preliminar...-mutations/563
Quote:
Mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2.
The spike deletion 69-70del has been described in the context of evasion to the human immune response but has also occurred a number of times in association with other RBD changes.
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It binds to our receptors better, and avoids the immune response better.
Evolution in action
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20-12-2020, 17:44
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#1823
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The Dark Satanic Mills
Join Date: Dec 2003
Location: floating in the ether
Posts: 13,234
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Re: Coronavirus
Quote:
Originally Posted by Mr K
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Well it didn’t bloody well parachute in did it? We are an island. If the new variant is here, the chances are it’s already in many other places.
__________________
The wheel's still turning but the hamsters dead.
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20-12-2020, 17:45
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#1824
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laeva recumbens anguis
Cable Forum Team
Join Date: Jun 2006
Age: 68
Services: Premiere Collection
Posts: 43,792
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Re: Coronavirus
Quote:
Originally Posted by Pierre
Well it didn’t bloody well parachute in did it? We are an island. If the new variant is here, the chances are it’s already in many other places.
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Mutations happen in situ, they don’t have to come from anywhere else.
The same mutation has been found in Denmark and Australia.
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20-12-2020, 17:47
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#1825
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The Dark Satanic Mills
Join Date: Dec 2003
Location: floating in the ether
Posts: 13,234
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Re: Coronavirus
Quote:
Originally Posted by Hugh
Mutations happen in situ, they don’t have to come from anywhere else.
The same mutation has been found in Denmark and Australia.
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Well done, you have both disagreed and agreed with me simultaneously!
__________________
The wheel's still turning but the hamsters dead.
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20-12-2020, 18:02
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#1826
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cf.mega poster
Join Date: Mar 2012
Posts: 4,108
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Re: Coronavirus
Quote:
Originally Posted by Mr K
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So Danish people aren't wanted either then?
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20-12-2020, 18:13
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#1827
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Woke and proud !
Join Date: Jun 2004
Services: TV, Phone, BB, a wife
Posts: 9,950
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Re: Coronavirus
Quote:
Originally Posted by Mad Max
So Danish people aren't wanted either then?
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You'll have to ask the countries concerned Max old chap.
We seem to have more cases and are more of an issue.
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20-12-2020, 18:21
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#1828
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laeva recumbens anguis
Cable Forum Team
Join Date: Jun 2006
Age: 68
Services: Premiere Collection
Posts: 43,792
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Re: Coronavirus
Quote:
Originally Posted by Pierre
Well done, you have both disagreed and agreed with me simultaneously!
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Apologies, I mis-read your post.
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20-12-2020, 19:27
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#1829
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Remoaner
Cable Forum Team
Join Date: Mar 2004
Posts: 32,864
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Re: Coronavirus
Well looks like the world is cutting us off!
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20-12-2020, 19:33
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#1830
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vox populi vox dei
Join Date: Mar 2007
Location: the last resort
Services: every thing
Posts: 14,823
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Re: Coronavirus
Quote:
Originally Posted by Damien
Well looks like the world is cutting us off!
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Bloody foreigners 
as long as the north pole don't cut us off before Christmas we'll be ok.
__________________
To be or not to be, woke is the question Whether 'tis nobler in the mind to suffer. The slings and arrows of outrageous wokedome, Or to take arms against a sea of wokies. And by opposing end them.
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