Coronavirus (OLD)

[richard s]

I am just getting over a bad cold... it was a bit worrying as my chest was sore on coughing, I also had a slight temperature and then the cold went to my head aka snot bag galore.


Back to work tomorrow (maintenance man at a care home).

[papa smurf]

Originally Posted by RichardCoulter

They won't want to damage the economy.

The virus seems to be sparing kids and killing the elderly/ill, leading conspiracy theorists to believe that this has been purposefully done to rid the world of chronically sick, disabled and elderly people who are no longer economically active.

Nature does that without any help.

[Taf]

One thing I've not heard a peep about during this "crisis" is the antiviral drug Tamiflu.

Originally Posted by RichardCoulter

They won't want to damage the economy.

The virus seems to be sparing kids and killing the elderly/ill, leading conspiracy theorists to believe that this has been purposefully done to rid the world of chronically sick, disabled and elderly people who are no longer economically active.

There are research teams at Liverpool working on this. Covid-19 has similarities with MERS (which IIRC is also a coronoavirus), which is fairly well understood - including the fact that it seems to be more dangerous in combination with certain other pathogens. It may turn out that older people, with weakened immune systems and greater exposure to the various microscopic nasties that exist, are thereby simply more susceptible.

---------- Post added at 20:52 ---------- Previous post was at 20:49 ----------

Originally Posted by Taf

One thing I've not heard a peep about during this "crisis" is the antiviral drug Tamiflu.

It’s not effective against Coronavirus. Tamiflu is designed to attack a specific feature of the influenza virus. Coronavirus is not influenza.

https://www.uchicagomedicine.org/for...an-coronavirus

[Dave42]

Steven Swinford
@Steven_Swinford
· 9m
EXCLUSIVE

Nadine Dorries, a health minister, has become first MP to be diagnosed with coronavirus

She has been in Westminster for past week, met hundreds of people, and attended a No 10 reception hosted by Boris Johnson on Thursday

https://thetimes.co.uk/article/coron...o-10-c3sjs5kmp

[RichardCoulter]

Originally Posted by Chris

There are research teams at Liverpool working on this. Covid-19 has similarities with MERS (which IIRC is also a coronoavirus), which is fairly well understood - including the fact that it seems to be more dangerous in combination with certain other pathogens. It may turn out that older people, with weakened immune systems and greater exposure to the various microscopic nasties that exist, are thereby simply more susceptible.

---------- Post added at 20:52 ---------- Previous post was at 20:49 ----------



It’s not effective against Coronavirus. Tamiflu is designed to attack a specific feature of the influenza virus. Coronavirus is not influenza.

https://www.uchicagomedicine.org/for...an-coronavirus

I read that they are finding that an HIV drug might be helpful:

https://www.fool.com/investing/2020/...treatment.aspx

Originally Posted by RichardCoulter

I read that they are finding that an HIV drug might be helpful:

https://www.fool.com/investing/2020/...treatment.aspx

Important to bear in mind, that with proper testing, it will still take at least a year and a half from inception to market release.

As Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases said last week

"A vaccine that you make and start testing in a year is not a vaccine that’s deployable,” he said. The earliest it would be deployable, Fauci added, is “in a year to a year and a half, no matter how fast you go.”

Also, from the same article

Shiver told me that the authority doesn’t expect to have anything ready for human trials until much later this year. “It’s difficult,” Shiver said, “to see how, even in the case of an emergency, a vaccine could be fully ready for licensure in a year and a half.”

https://www.newyorker.com/news/news-...avirus-vaccine

[jonbxx]

Originally Posted by RichardCoulter

I read that they are finding that an HIV drug might be helpful:

https://www.fool.com/investing/2020/...treatment.aspx

There is some brilliant science going on with this at the moment, screening compounds by computer simulation to find potential inhibitors. In this study, 687 million compounds were screened in silico to come up with 17 potential drugs for real world testing including an anti ovarian cancer drug. This study pulled up 10 commercial drugs including heart, cancer and antipsychotic drugs.

Of course, computer simulations are one thing, the results may vary in the real world but there is potential out there before any vaccine comes on line

[pip08456]

Originally Posted by jonbxx

There is some brilliant science going on with this at the moment, screening compounds by computer simulation to find potential inhibitors. In this study, 687 million compounds were screened in silico to come up with 17 potential drugs for real world testing including an anti ovarian cancer drug. This study pulled up 10 commercial drugs including heart, cancer and antipsychotic drugs.

Of course, computer simulations are one thing, the results may vary in the real world but there is potential out there before any vaccine comes on line

Of course you and others can help with this and other studies too.

https://www.worldcommunitygrid.org/d...on#comparisons

[SnoopZ]

My place of work is going into 'coronavirus mitigation plans' meaning they're trying to build what they can quickly for customer orders(probably not possible as it takes days/weeks to build a digital printhead through the line) as they fully expect a government shutdown, if only 1 person shows signs of the virus we will get shut down as i work in a cleanroom, scary time!

[denphone]

The Public Health England Covid-19 cases tracker is a useful tool.

https://www.arcgis.com/apps/opsdashb...0b19484dd4bb14

[joglynne]

The Lancet has published the following

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

Bit of a long read but interesting to see the breakdown of the findings based on the earliest group to contract COVID 19.

https://www.thelancet.com/pb-assets/...7362305663.pdf

[jonbxx]

Originally Posted by SnoopZ

My place of work is going into 'coronavirus mitigation plans' meaning they're trying to build what they can quickly for customer orders(probably not possible as it takes days/weeks to build a digital printhead through the line) as they fully expect a government shutdown, if only 1 person shows signs of the virus we will get shut down as i work in a cleanroom, scary time!

Our work has banned all 'non business critical' travel globally and has stopped all attendances at exhibitions and conferences. I reckon we're not far away from most office based people to be told to work from home where possible (makes no difference to me as I work from home all the time anyway)

Manufacturing will continue though, even in China, as the business I am in is directly related to healthcare.

[denphone]

Eighth British citizen dies from coronavirus.

https://www.theguardian.com/world/li...087df56e4c64c5

[nomadking]

Originally Posted by denphone

Eighth British citizen dies from coronavirus.

https://www.theguardian.com/world/li...087df56e4c64c5

The more relevant issue is where there are, not citizenship. Deaths in Indonesia or Japan are issues for those countries.