I presume that you haven't changed any settings....
Does your work restrict ip addresses that can connect to the VPN server? if so it is possible that your ip changed and this is causing problems.
What error do you get when your trying to connect? And also, what type of VPN connection is it...? Infact, do you know any technical information about the connection*
Also, are you using windows XP? Any firewall software on the PC? and does the router have VPN passthrough setup?
*NB- this is not meant to sound patronising- but i know lots of people who use VPN connections, but know nothing about them, just rely on the IT dept! Forgive me if you are not one of these people...