Thread: Coronavirus
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Old 13-10-2021, 21:32   #7579
Hugh
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Re: Coronavirus

Quote:
Originally Posted by Pierre View Post
Yes interesting one this, Merck that also produced Ivermectin that was reported to alleviate COVID hospitalization and deaths but has been rubbished left right and centre and ‘no evidence’. Etc etc. Merck’s patent on Ivermectin has ran out meaning it can be produced for about £5 a dose.

But now Merck have produced a new drug “Molnupiravur” which is totally effective against COVID and nothing like Ivermectin guvenor oh no, this is the proper stuff you want.

Price for you? I can do it for £750 a dose.

Good news for all those born yesterday.
For those born today, here is the reality, not the Internet conspiracy theory…

https://www.reuters.com/article/fact...-idUSL1N2R32JP
Quote:
Dr. Stephen Griffin, virologist and associate professor at the University of Leeds (here), told Reuters that molnupiravir is not repackaged ivermectin.

The two drugs have “dissimilar chemistry,” he said. “There is no way that Merck is doing this,” he said.

“Molnupiravir is a derivative of a nucleotide that, predictably, interferes with the RNA replication of the virus. While Ivermectin does also have a defined mechanism of action, BUT it’s against ion channels found in parasites,” Griffin said.

Information profiles are viewable on Drugs.com for molnupiravir (here) and ivermectin (www.drugs.com/ivermectin.html).

Paul Auwaerter, the Clinical Director of the Division of Infectious Diseases (here) at Johns Hopkins Medicine told Reuters via email that the only similarity the two drugs have is that they “have been brought to the FDA for market approval by the Merck Company.”

The professor pointed to structural differences between the two drugs, which can be explored in papers here and here and drug class differences. “Ivermectin is classified as a macrocyclic lactone. It is derived from Streptomyces avermitilis which is a bacterium." Molnupiravir, rather, is classified as a nucleoside analog (like some HIV medications) and works as an antiviral, he said.
Strangely enough, exactly the same Bolleaux was being spread about the Pfizer anti-viral treatment when it was announced a couple of days before the Merck announcement, then the tinfoil milliners seamlessly swivelled to spread the same ordure about Merck.
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Last edited by Hugh; 13-10-2021 at 21:36.
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