I started having problems with this update. NTBackup freezing and a program called ExplorerPlus also freezing. Also found several copies of a new file in the task list, "Verclsid.exe".
After searching, found
this and
this. Apparently, one of the security fixes does break some programs and Windows itself (such as Windows freezing when right-clicking on desktop). The main problem is with HP printer and scanner drivers, but it can cause problems when no HP drivers are installed.
Personally, the fix I've used is to rename the "C:\Windows\System32\Verclsid.exe" file to "C:\Windows\System32\Verclsid.old" which seems to work okay. However, these workarounds do kill the security fix so should only be used if you have problems.