Quote:
Originally Posted by jfman
I'm interested in the rationale to reduce the period from 12 to 8 weeks between vaccination when previously the logic was it makes more sense to give more people some kind of vaccine.
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The difference in efficacy between one and two doses is turning out to be wider in real-life than it was in trials (they only used a 3 week gap in trials). Most 40-somethings have now had their first dose, so I presume they have calculated giving the over-50s their second dose early is more beneficial than starting on the 30-somethings.
This is despite a 12-week gap probably being more effective than an 8-week one. I suspect dose #3 will be along fairly soon after to make up the difference.