[Sephiroth]

Originally Posted by jonbxx

Yeah, I (happily) left my statistics behind a looong time ago! I read the confidence interval as -1405 to 94.2%. Obviously a negative efficacy would mean that the vaccine made you more susceptible to COVID which isn't really where we want to be going with a vaccine.

The elephant in the room is the control group showing 1/319 against the 1/341 for the dosed group.

I think there's something missing datawise. If this is the total of the submitted data to the EMA/EU countries, I can understand the reasoning for the stopping of doses for the elderly - why give it to them if it doesn't work and there are alternatives. Unfortunately, regulatory submissions are very much not public domain

Ah yes - of course. Nevertheless, a sample result of 1 cannot provide a sensible confidence level unless there were other corroborative data.