Quote:
Originally Posted by Sephiroth
I do quite a bit of statistical work in my line of business.
The confidence interval in the AZ data is entirely negative and that's because there is no range of results that could fall within the entirely negative interval. The 1/314 result of the study is of insufficient statistical significance.
It seems to me as a layman in the epidemiology business that 1/314 is heading in the right direction.
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Yeah, I (happily) left my statistics behind a looong time ago! I read the confidence interval as -1405 to 94.2%. Obviously a negative efficacy would mean that the vaccine made you more susceptible to COVID which isn't really where we want to be going with a vaccine.
The elephant in the room is the control group showing 1/319 against the 1/341 for the dosed group.
I think there's something missing datawise. If this is the total of the submitted data to the EMA/EU countries, I can understand the reasoning for the stopping of doses for the elderly - why give it to them if it doesn't work and there are alternatives. Unfortunately, regulatory submissions are very much not public domain
