Thread: Coronavirus
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Old 18-01-2021, 11:11   #2931
richard s
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Re: Coronavirus
Quote:
Originally Posted by jonbxx View Post
Just catching up on this thread and have seem some vaccine hesitancy here, much like in the larger population. I have seem comments here questioning the safety of the vaccines due to the speed of the roll out, questioning the sample (cohort) size and lack of long term safety information.

The questions I would ask are these;
  • What is a satisfactory cohort size to convince the doubters that a drug is safe?
  • What is the basis on which this number is reached?
  • How long is long enough to judge that there are no long term effects and again, what is this based on?
  • Do doubters look at trial data for other drugs on the market to judge sufficient trial robustness?
  • If not, why not? What is special about this vaccine?
  • Is there still confidence in drug safety evaluation performed by regulatory agencies in light if the speed of approval for COVID vaccines?

This article gives data in table 1 on the cohort sizes for a number of vaccines approved by the FDA from 2000-2011. Some of the cohorts are pretty small! - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551877/



I have had the the injection on the 17/12/2020 because I did work in a care home. No side effects yet.
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