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Re: U.S Election 2020
Quote:
Originally Posted by 1andrew1
The FT said there were actually two errors in the memo:
b) An incorrect name was used for the drug itself. The memo of 3rd October refers to it as a polyclonal antibody therapy whilst Regeneron's antibody therapy is monoclonal. Not an expert on the differences here eg if a cocktail is used, does it become "poly"?
b) Manufacturer's name, using the name Regeron instead of Regeneron. (Regeron focuses on reverse-aging biotechnology, especially on manufacturing human polypeptide growth factors for cosmetic applications including hair care).
A potential typo or genuine confusion with the other company.
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Quote:
Originally Posted by pip08456
Polyclonal is a mixture of T3 antibody cloned genes. Monoclonal uses the same cloned T3 antibody gene.
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Quote:
Originally Posted by 1andrew1
Thanks, an important difference then.
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Quote:
About REGN-COV2
REGN-COV2 is a combination of two monoclonal antibodies (REGN10933 and REGN10987) and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19.
To develop REGN-COV2, Regeneron scientists evaluated thousands of fully-human antibodies produced by the company's VelocImmuneŽ mice, which have been genetically modified to have a human immune system, as well as antibodies identified from humans who have recovered from COVID-19. The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science. Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.
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https://investor.regeneron.com/news-...ral-levels-and
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Last edited by Hugh; 04-10-2020 at 12:47.
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