[Sephiroth]

Originally Posted by Damien

I think it was designed to defeat immunity we would have seen evidence of that by now. It seems we do develop an immune response thankfully.

That would be excellent news but I haven't seen definitive proof that we have immunity after infection or vaccine but see below.

Some useful news is given in a paper at https://blogs.sciencemag.org/pipelin...he-coronavirus

Mixed into that useful news is an explanation of why older folk are at greater risk of having a really difficult time (cytokine storm).

It's the first article I've seen that gets down to to the cellular type level and its effect on CV.

Key concluding paragraph quoted below:

So overall, this paper makes the prospects for a vaccine look good: there is indeed a robust response by the adaptive immune system, to several coronavirus proteins. And vaccine developers will want to think about adding in some of the other antigens mentioned in this paper, in addition to the Spike antigens that have been the focus thus far. It seems fair to say, though, that the first wave of vaccines will likely be Spike-o-centric, and later vaccines might have these other antigens included in the mix. But it also seems that Spike-protein-targeted vaccines should be pretty effective, so that’s good. The other good news is that this team looked for the signs of an antibody-dependent-enhancement response, which would be bad news, and did not find evidence of it in the recovering patients (I didn’t go into these details, but wanted to mention that finding, which is quite reassuring). And it also looks like the prospects for (reasonably) lasting immunity after infection (or after vaccination) are good. This, from what I can see, is just the sort of response that you’d want to see for that to be the case. Clinical data will be the real decider on that, but there’s no reason so far to think that a person won’t have such immunity if they fit this profile.