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Old 19-05-2020, 13:49   #3474
Hugh
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Re: Coronavirus

Quote:
Originally Posted by downquark1 View Post
This hydroxychloroquine stuff is really eye opening, they sell boat loads of it to Africa for Malaria but suddenly it's the most dangerous substance on earth.
"for Malaria*" is the crux of the matter, not for COVID-19 - in fact, the European Medicines Agency stated last month

Quote:
Chloroquine and hydroxychloroquine are known to potentially cause heart rhythm problems, and these could be exacerbated if treatment is combined with other medicines, such as the antibiotic azithromycin, that have similar effects on the heart.

Recent studies1,2 have reported serious, in some cases fatal, heart rhythm problems with chloroquine or hydroxychloroquine, particularly when taken at high doses or in combination with the antibiotic azithromycin.

Chloroquine and hydroxychloroquine are currently authorised for treating malaria and certain autoimmune diseases. In addition to side effects affecting the heart, they are known to potentially cause liver and kidney problems, nerve cell damage that can lead to seizures (fits) and low blood sugar (hypoglycaemia).

These medicines are being used in the context of the ongoing pandemic for treating patients with COVID-19 and investigated in clinical trials. However, clinical data are still very limited and inconclusive, and the beneficial effects of these medicines in COVID-19 have not been demonstrated. Results from large, well-designed studies are needed to make any conclusions.

Some clinical trials currently investigating the effectiveness of chloroquine or hydroxychloroquine in treating COVID-19 use higher doses than those recommended for the authorised indications. While serious side effects can occur with recommended doses, higher doses can increase the risk of these side effects, including abnormal electrical activity that affects the heart rhythm (QT-prolongation).
There is no consistent scientific proof this will prevent COVID-19 (and small mixed results on treating COVID-19 infection).



*treating malaria, not preventing it, also to treat lupus and rheumatoid arthritis
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Last edited by Hugh; 19-05-2020 at 13:53.
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