Iv`e never done it but can`t see any reason why there could be a problem. After all it`s just a serial number which ties you into the product and has an expiry date.
Remember that you can normally buy a new copy for less than the price of a renewal of your subscription, depending on the product.
NIS 2010 OEM here for £13 for example
http://www.aria.co.uk/Products/Softw...roductId=38024