If you are using TruImage and only have a single HDD don't forget about making a backup to a Protected Partition. Simply activate the "Manage Secure Zone" wizard and follow the prompts to create a protected location to save to. Using this method a back up of the Operating system only takes about 20 minutes.
Other possibilities for back up locations are creating a new "Data" partition or acquiring an external HDD.
Of course if your internal HDD goes down so does your backup.
External HDD's are relatively cheap and so get my vote.