The only problem I've ever had with trying to run 2 sound cards, was the joystick port...
The mobo has built in audio, but no joystick port on the backplane.
The soundcard I tried (Trust 514DX) had a joystick port, but clashed with a 'ghost' port that couldn't be turned off on the mobo, even with the internal audio disabled in the bios.
Not a biggie - the joystick is fine via usb, I just thought I'd share
