Nod32 here.Never had any problems with it in three years.As someone who frequently wants all the memory I can get, to render art work I find it excellent as it uses so few resources.
As for not having an AV at start up,that does seem like asking for trouble.With my memory I'd forget to check I had an AV running.
I'm sure someone will remind me how quickly a new clean PC connected to the net can become infected.
Oh and did Neil ever give out the results on his experimental PC to see how soon and how often it would get infected?