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Originally Posted by Xaccers
It's not likely that the kidney cells mutated during development in the womb for both brothers.
More likely that the genes that produce the "make a kidney" protein are doubled up.
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Wich gives it about a 50% chance of it being inherrited by thier children (ish, I cant remember how you work it out, though I know the chances are increased considderably if both parents have the mutation)