.NET CAS Settings Problem
 

I have a VB .NET app which is intended to run from a server. In order to get this to work ive changed the .NET CAS settings to allow applications to run in the Intranet zone. However ive had the following results from some tests


Machine 1, User 1 = Works
Machine 1, User 2 = Fails
Machine 2, User 1 = Fails
Machine 2, User 2 = Fails

In the failure instances if i change the .NET CAS settings to allow applications to run in the Internet zone it appears to work, however this is not an acceptable solution.

Any bright ideas? Seems to me that here might be 2 issues, one with user 2's policies and one with machine 2's policies. However it might be something simpler that ive over looked. What i dont understand is why .NET thinks the application has changed zone between users.