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jfman 26-11-2020 21:19
Re: Coronavirus
 
Quote:
Originally Posted by Sephiroth (Post 36059905)
Yes that's right. I want a vaccine that has no ability to induce an auto-immune response. I'll have to check with my GP about all that.

It seems that the Oxford vaccine meets my requirement. The Pfizer vaccine seems to have seriously active components being RNA based.

Useful comparison is at https://www.expressandstar.com/news/...er-to-pfizers/.
I just want one that works so 70% or so of other people can take it and I don't need to. :)

(I'm joking)

Sephiroth 26-11-2020 21:22
Re: Coronavirus
 
Quote:
Originally Posted by jfman (Post 36059907)
I just want one that works so 70% or so of other people can take it and I don't need to. :)

(I'm joking)
Well that was a waste of effort then!

(Just joking).

jonbxx 27-11-2020 09:38
Re: Coronavirus
 
Quote:
Originally Posted by Sephiroth (Post 36059905)
Yes that's right. I want a vaccine that has no ability to induce an auto-immune response. I'll have to check with my GP about all that.

It seems that the Oxford vaccine meets my requirement. The Pfizer vaccine seems to have seriously active components being RNA based.

Useful comparison is at https://www.expressandstar.com/news/...er-to-pfizers/.
The Oxford vaccine is DNA based however. Gut feeling with out evidence makes me more comfortable to the mRNA vaccines than the AZ/Oxford vaccine for two reasons;
  • mRNA has a shorter half life in the cell (minutes to hours) compared with adenoviral DNA so the vaccine gets in, does its job and is gone
  • The mRNA vaccines are synthetic rather than being based on live virus. I know primate adenovirus shouldn't affect humans but there's a small worry in the back of the head on this

Based on nothing of course and if the only option were adenoviral vaccines like the AZ/Oxford one then jab me up but if I had a choice, I would prefer the BioNTech/Pfizer one

Sephiroth 27-11-2020 09:46
Re: Coronavirus
 
Very useful that someone on the forum knows their stuff in this regard.

heero_yuy 27-11-2020 10:21
Re: Coronavirus
 
Quote:
Quote from The Sun: Chris Whitty has refused to support the AstraZeneca coronavirus vaccine as the pharmaceutical giant vows to run a new Oxford vaccine trial after a "lower dose error".

The Government's Chief Medical Adviser dodged giving the AstraZeneca jab his support during Thursday evening's press conference amid controversy with data from its late-stage trials.

The country's top doctor said judgement of the vaccine's efficacy and safety should "left in the hands" of Britain's drug watchdog.
Lizard-man doom-monger ain't convinced. :erm:

papa smurf 27-11-2020 10:27
Re: Coronavirus
 
Quote:
Originally Posted by heero_yuy (Post 36059939)
Lizard-man doom-monger ain't convinced. :erm:
Or has he got shares in another vaccine.

Hugh 27-11-2020 10:28
Re: Coronavirus
 
Quote:
The country's top doctor said judgement of the vaccine's efficacy and safety should "left in the hands" of Britain's drug watchdog
Sounds like an eminently reasonable and sensible statement - let the organisation whose job it is to approve these things decide whether to approve these things.

Damien 27-11-2020 10:38
Re: Coronavirus
 
Yeah let the regulators deal with it and ignore the Americans who are probably just trying to sell the American public on why they need to pay 4x as much as Europeans for their vaccine.

jfman 27-11-2020 11:59
Re: Coronavirus
 
Quote:
Originally Posted by jfman (Post 36059903)
While I'm equally sceptical of American input/insight into anything trade related as they'll have obvious protectionist tendencies and they have another dog in this race I look forward to more data and peer review to clear matters up.

I'm sure we all want a vaccine that works, and not just the cheapest one we can drape in a Union Flag.
https://www.huffingtonpost.co.uk/amp...k_5fbfdd14c5b6

When I initially posted this it was a turn of phrase. I suppose we have a Government beyond parody.

Chris 27-11-2020 12:44
Re: Coronavirus
 
Quote:
Originally Posted by papa smurf (Post 36059940)
Or has he got shares in another vaccine.
Or he understands the proper process better than Sun hacks who earn a living asking loaded questions.

It isn’t the Chief Medical Adviser’s job to endorse a medicine that hasn’t completed assessment and certification. In fact doing so could be construed as interference in that process.

Of course that won’t stop red-top tabloids from scoring a cheap headline by making it look like he’s equivocating.

1andrew1 27-11-2020 13:28
Re: Coronavirus
 
Quote:
Originally Posted by jfman (Post 36059965)
https://www.huffingtonpost.co.uk/amp...k_5fbfdd14c5b6

When I initially posted this it was a turn of phrase. I suppose we have a Government beyond parody.
https://www.huffingtonpost.co.uk/ent...b68ca87f827a0e

Revised link above as yours is broken.

Ha ha. :D

I've read the British government's policy is to coat anything they've funded with the Union Jack in the same way that the EU flag was used for EU funded projects. I'm not sure it worked out well for the EU. ;)

---------- Post added at 13:28 ---------- Previous post was at 12:50 ----------

Good article here on how the tiers were arrived at.
https://www.bbc.co.uk/news/54250626

Carth 27-11-2020 13:42
Re: Coronavirus
 
I always thought EU funded projects were draped with the Skull & Crossbones ;)

1andrew1 28-11-2020 21:26
Re: Coronavirus
 
Some very good news and credit to the Government's efforts here.
Quote:
The UK is poised to become the first western country to approve a Covid-19 vaccine, with the independent regulator set to grant approval within days.

Deliveries of the vaccine developed by BioNTech and Pfizer would begin within hours of the authorisation, according to government officials. The first injections could take place from December 7.

The UK has ordered 40m doses of the two-shot product, which preliminary data found to be more than 95 per cent effective in preventing disease.

Vaccines would normally be authorised by the European Medicines Agency until the end of the Brexit transition on December 31. However the UK’s Medicines and Healthcare Products Regulatory Agency has the power to temporarily authorise products, in cases of urgent public need.

The same process could be applied to the vaccine developed by AstraZeneca and Oxford university. On Friday, the government wrote to the regulator, asking it to review the AstraZeneca-Oxford vaccine.

Russia approved a coronavirus vaccine in August, but this was not based on large-scale trial data.
https://www.ft.com/content/ebd9ca50-...5-e90e93c0c495

jfman 29-11-2020 00:31
Re: Coronavirus
 
Quote:
Originally Posted by Carth (Post 36059988)
I always thought EU funded projects were draped with the Skull & Crossbones ;)
There's a flag I can toast a rum to!

pip08456 29-11-2020 11:19
Re: Coronavirus
 
1st doses of Pfizer vaccine flown to US.


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