Cable Forum

Cable Forum (https://www.cableforum.uk/board/index.php)
-   Current Affairs (https://www.cableforum.uk/board/forumdisplay.php?f=20)
-   -   Coronavirus (https://www.cableforum.uk/board/showthread.php?t=33709417)

Pierre 05-04-2021 22:40

Re: Coronavirus
 
Quote:

Originally Posted by Sephiroth (Post 36076292)
Careful Pierre - OB's not posting very often and jfman needs someone with whom to argue!

JFman, along with many others is part of the rich tapestry of CF, and we’d be poorer without him. No matter how much he melts your head.

However


Quote:

Originally Posted by jfman (Post 36076291)
There’s unused vaccine everywhere, simply because it doesn’t go from plant to arm in a seamless process. They’ve bought and paid for them. For the “strategy” to work it has to be manufactured by but not purchased in favour of other vaccines despite widespread availability.

But you appear to be ignoring the very much reported issue of people demonstrably rejecting the AZ vaccine due to the info-war against it. Nothing to do with supply chain or logistics, people outrightly refusing to take it for fear of Blood clots, or it just not working.

Quote:

Other developers perhaps, but the accusation was levelled at politicians.
politicians working for or responding to, lobbyists from other vaccine developers not yet in the game.

Quote:

So we are back at rational capitalists wanting to delay and spend more on vaccines in the long run. :confused:
no...politicians, wanting to alter the,aging field so that vaccine developers they represent get a slice of the pie.

jfman 05-04-2021 22:56

Re: Coronavirus
 
I’m not sure people are refusing it in significant enough numbers to make money for other vaccine developers.

Your accusation seems to be that politicians in the US and Europe are corrupt, but only in the hands of pharmaceutical companies they represent. I’d contest that such widespread corruption in favour of corporate interests is just as likely (if not moreso) to come from the tens of (hundreds of) billions of pounds/dollars/euro at risk outside the the pharmaceutical sector. Boeing and Airbus can’t be too happy with all these planes not running up mileage.

jfman 06-04-2021 08:27

Re: Coronavirus
 
Channel 4 News reporting that restrictions could be made on the AZ vaccine in the UK on under 30s but the MHRA saying “no decision has been made”.

https://www.theguardian.com/uk-news/...-for-under-30s

The Guardian even dug up Professor Pantsdown for a quote. I’m sure the story over the weekend about giving people in their 20s the J&J vaccine “to allow them to get one shot and jet off on holiday” is conveniently timed and 100% unlinked.

papa smurf 06-04-2021 08:34

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076304)
Channel 4 News reporting that restrictions could be made on the AZ vaccine in the UK on under 30s but the MHRA saying “no decision has been made”.

https://www.theguardian.com/uk-news/...-for-under-30s

The Guardian even dug up Professor Pantsdown for a quote.

Looks like some other vaccine manufacturer could get a slice of the pie £

jfman 06-04-2021 08:38

Re: Coronavirus
 
Quote:

Originally Posted by papa smurf (Post 36076305)
Looks like some other vaccine manufacturer could get a slice of the pie £

Indeed, with good honest UK politicians and regulators making the decision we can be 100% confident that there’s no corruption in their processes. No drinking buddies, party donors etc. The sort of thing you’d expect from Europe.

Sephiroth 06-04-2021 08:57

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076306)
Indeed, with good honest UK politicians and regulators making the decision we can be 100% confident that there’s no corruption in their processes. No drinking buddies, party donors etc. The sort of thing you’d expect from Europe.

From Europe I expect to find Merkel’s convenient discard, VDL, who couldn’t sort out the corruption in her Defence Ministry’s contracts.


Edit; Also Sarkozy who is doing time for corruption.

jonbxx 06-04-2021 09:05

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076304)
Channel 4 News reporting that restrictions could be made on the AZ vaccine in the UK on under 30s but the MHRA saying “no decision has been made”.

https://www.theguardian.com/uk-news/...-for-under-30s

The Guardian even dug up Professor Pantsdown for a quote. I’m sure the story over the weekend about giving people in their 20s the J&J vaccine “to allow them to get one shot and jet off on holiday” is conveniently timed and 100% unlinked.

How quickly will AstraZeneca become a Swedish company if the vaccine is restricted. Much like Andy Murray is Scottish when he loses and British when he wins

jfman 06-04-2021 09:19

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076308)
How quickly will AstraZeneca become a Swedish company if the vaccine is restricted. Much like Andy Murray is Scottish when he loses and British when he wins

Nah, their place in the great British success story is cemented as long as we avoid a deadly fourth wave.

I do hope they get to the bottom of the risk factors around clotting issue though - if this has to turn into an annual vaccine safety will be paramount to public confidence and "emergency use" is an easy decision knee deep in a pandemic, it might not always be so straightforward.

Carth 06-04-2021 09:54

Re: Coronavirus
 
There's a risk factor in everything we do, and we need to look at the risk of death/serious illness from a blood clot, as opposed to the risk of death/serious illness from catching Covid.

In the current state of things, we also need to factor in the difference between having the vaccination or not, which introduces a greater risk of transmission to others from those who don't vaccinate (and also a probably reduced lifestyle for those who don't).

I think it's developing into a 'bark is worse than the bite' scenario, where people are more concerned about a possible blood clot than catching & transmitting Covid ;)

Regarding the yearly vaccination, by that time we will (hopefully) have better figures on the vaccine and it's side effects.

Chris 06-04-2021 10:19

Re: Coronavirus
 
30 cases out of 18 million really ought to be re-stated every time this is discussed, because some of the commentary around this is starting to make it sound like taking the AZ vaccine is Russian roulette.

If there is a direct causal link then the odds of getting a blood clot from the vaccine are still ridiculously low. If there is a direct causal link, then some of the reported cases will still not have been caused by the vaccine because these things occur naturally in the population at a low rate anyway.

The danger here is that we talk ourselves into losing confidence in the vaccine for no other reason that talking about the latest covid-related gossip is now the national pastime.

If I were a betting man, I’d bet that the single-dose J&J vaccine is offered to younger people, and that the official advice underpinning that is that this is a harder-to-reach age group and a single vaccine is therefore advantageous. That will allow AZ to be restricted from the age group where it *might* pose an identifiable risk, without there being any loud public statements that undermine overall confidence in the AZ vaccine.

Meanwhile, as research continues, if there is a link, then it ought to be possible to identify why one vaccine causes clots and another doesn’t. Vaccines can and do get reformulated when necessary.

jfman 06-04-2021 10:35

Re: Coronavirus
 
I don't think there's any doubt about the fact there's an identifiable risk given it's independently noted in the UK, Germany and others.

The question is whether it's an acceptable risk, which for a vaccination programme by consent hits problems for the members of the public who have been told they are extremely low risk of Covid complications anyway.

jonbxx 06-04-2021 10:49

Re: Coronavirus
 
Quote:

Originally Posted by Chris (Post 36076312)
30 cases out of 18 million really ought to be re-stated every time this is discussed, because some of the commentary around this is starting to make it sound like taking the AZ vaccine is Russian roulette.

If there is a direct causal link then the odds of getting a blood clot from the vaccine are still ridiculously low. If there is a direct causal link, then some of the reported cases will still not have been caused by the vaccine because these things occur naturally in the population at a low rate anyway.

The danger here is that we talk ourselves into losing confidence in the vaccine for no other reason that talking about the latest covid-related gossip is now the national pastime.

If I were a betting man, I’d bet that the single-dose J&J vaccine is offered to younger people, and that the official advice underpinning that is that this is a harder-to-reach age group and a single vaccine is therefore advantageous. That will allow AZ to be restricted from the age group where it *might* pose an identifiable risk, without there being any loud public statements that undermine overall confidence in the AZ vaccine.

Meanwhile, as research continues, if there is a link, then it ought to be possible to identify why one vaccine causes clots and another doesn’t. Vaccines can and do get reformulated when necessary.

Pretty much this - if there is a small risk of increased clotting events in certain populations and there are enough vaccines of different types to go around, then recommending AZ for those at a lower risk and Pfizer, Janssen, Moderna and Novavax for everyone else seems sensible.

That said, if you're in an 'at risk' group for clotting events and already have had your first shot of AZ, not sure what's going to happen there - mix and match or take the risk of a second shot of AZ?

jfman 06-04-2021 12:03

Re: Coronavirus
 
Suspect they'll apply the logic that they didn't get complications the first time and it's extremely rare rather than introduce mix and match.

1andrew1 06-04-2021 12:10

Re: Coronavirus
 
Quote:

COVID-19: UK-made Valneva coronavirus vaccine produces 'strong immune response' in early trials, says Matt Hancock
https://news.sky.com/story/covid-19-...ncock-12267367

Pierre 06-04-2021 13:46

Re: Coronavirus
 
Quote:

Originally Posted by Chris (Post 36076312)
30 cases out of 18 million really ought to be re-stated every time this is discussed, because some of the commentary around this is starting to make it sound like taking the AZ vaccine is Russian roulette.

If there is a direct causal link then the odds of getting a blood clot from the vaccine are still ridiculously low. If there is a direct causal link, then some of the reported cases will still not have been caused by the vaccine because these things occur naturally in the population at a low rate anyway.

The danger here is that we talk ourselves into losing confidence in the vaccine for no other reason that talking about the latest covid-related gossip is now the national pastime.

If I were a betting man, I’d bet that the single-dose J&J vaccine is offered to younger people, and that the official advice underpinning that is that this is a harder-to-reach age group and a single vaccine is therefore advantageous. That will allow AZ to be restricted from the age group where it *might* pose an identifiable risk, without there being any loud public statements that undermine overall confidence in the AZ vaccine.

Meanwhile, as research continues, if there is a link, then it ought to be possible to identify why one vaccine causes clots and another doesn’t. Vaccines can and do get reformulated when necessary.

30 cases out of 18million subjects is lower than what you expect in the general population.

I wonder how many people have fallen and broken their arm since having the vaccine? No doubt there could causal relationship between the vaccine and broken limbs if you looked hard enough.

jfman 06-04-2021 13:54

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076329)
30 cases out of 18million subjects is lower than what you expect in the general population.

I wonder how many people have fallen and broken their arm since having the vaccine? No doubt there could causal relationship between the vaccine and broken limbs if you looked hard enough.

It isn’t though, that’s why almost everyone is investigating.

Incidence of these rare blood clots could be as low as 2 per million in a 12 month period. Germany is seeing a higher incidence than the UK, as are other EU nations who based on their hapless vaccine rollout wouldn’t expect to see any at all.

The uneven distribution by age, sex, presumably is making it even more noteworthy.

1andrew1 06-04-2021 14:04

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076329)
30 cases out of 18million subjects is lower than what you expect in the general population.

I wonder how many people have fallen and broken their arm since having the vaccine? No doubt there could causal relationship between the vaccine and broken limbs if you looked hard enough.

The key thing is the blood clots have not occurred with the other Covid 19 vaccines.

I looked into why other countries throughout the world were being so cautious. One element is that they have a far higher level of vaccine scepticism - polls in France suggest half the population may decline a vaccine. So, unless statistically small issues are exhaustively investigated, populations may refuse the vaccine even if it is rolled out. Waiting and investigating may result in a higher uptake rate.

jfman 06-04-2021 14:17

Re: Coronavirus
 
It’ll be a good one for the public inquiry to find out what the MHRA knew and when under their “yellow card” scheme. It would seem odd for a statistically significant deviation to be observed in the hapless EU programme but not first emerge in the world beating UK vaccination programme.

jonbxx 06-04-2021 15:05

Re: Coronavirus
 
It's good at least to see that the vigilance systems work. From the noises of various regulatory bodies, it seems like women under 50 are at a higher than normal risk. Of course, the UK has been working on the oldest most vulnerable populations first so significant numbers in the UK may not have popped up until now.

If I have time later, I might have a look at Norway's vaccine prioritisation process to see if health workers or teachers were prioritised earlier which would then have exposed a much younger cohort earlier than the UK's process.

Pierre 06-04-2021 15:48

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076330)
It isn’t though, that’s why almost everyone is investigating.

Incidence of these rare blood clots could be as low as 2 per million in a 12 month period.

As low as two or as high a five per million that means, using 18million as a stake in the ground, but obviously the vaccinated number will go up, that you would expect to see anywhere between 36 - 90 cases, in that cohort of 18 million naturally.

Quote:

The uneven distribution by age, sex, presumably is making it even more noteworthy.
As Chris pointed out some weeks ago, it seems to be young women affected mostly. A section most likely to take contraception pills, that also cause blood clots as a side affect.

https://www.stoptheclot.org/about-cl...control_clots/

---------- Post added at 15:48 ---------- Previous post was at 15:38 ----------

Quote:

Originally Posted by 1andrew1 (Post 36076331)
The key thing is the blood clots have not occurred with the other Covid 19 vaccines.

That is not correct

Quote:

In the U.S., a Miami physician died following complications of immune thrombocytopenic purpura (ITP) after his first dose of the Pfizer COVID-19 vaccine. ITP is a rare autoimmune condition in which the body generates autoantibodies to its own platelets, resulting in low platelet counts, blood clots, and bleeding if the platelet count drops very low. About 50,000 adults are diagnosed with ITP in the U.S. per year. Risk is increased in young women and people with other autoimmune conditions.

In a case series, James Bussel, MD, and colleagues reviewed 20 reports of thrombocytopenia after receipt of the Pfizer and Moderna COVID-19 vaccines in the U.S. Bussel is professor emeritus of pediatrics at Weill Cornell Medical College in New York City who has published extensively on ITP. His group found that 17 of these patients did not have pre-existing thrombocytopenia. Patients' median age was 41 and 11 were women.

"It is not surprising that 17 possible de novo cases would be detected among the well over 20 million people who have received at least one dose of these two vaccines in the United States as of February
https://www.medpagetoday.com/special...clusives/91813

More investigations are required but I would think it is still too early to put a causal link to these issues at the hands of the vaccines.

jfman 06-04-2021 16:06

Re: Coronavirus
 
Even if it were as high as 5 per million you're not factoring in the likelihood of it happening within X (MHRA haven't gone public with this) days of vaccination among a subset vaccinated between the start of January and March 23 (or whatever the cutoff the MHRA still use).

The cohort size hasn't permanently been 18 million - it's rising over time so analysis is more complicated.

You're also conflating blood clots in general with the rare type being seen here. If there is evidence that, linked with the contraceptive pill or other medication, the risk is higher than a vaccination programme by consent has to be open and transparent about what the risks are. Not wrap them up in a Union Flag and blame the dastardly EU.

Taf 06-04-2021 16:47

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076329)
30 cases out of 18million subjects is lower than what you expect in the general population.

A bit of lateral thinking: what if the vaccine is REDUCING the chance of a brain clot? The incidence has greatly reduced from what is normally seen.

:dunce:

jonbxx 06-04-2021 16:52

Re: Coronavirus
 
Wow, had a quick look at the 'Yellow card' reporting for the COVID vaccines. It seems a LOT of people report side effects!

Have fun with the reports for Pfizer and AZ

Someone apparently vomited themselves to death after the AZ vaccine. Nasty (and NOT a definite link at this point)

Sephiroth 06-04-2021 17:05

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076344)
Wow, had a quick look at the 'Yellow card' reporting for the COVID vaccines. It seems a LOT of people report side effects!

Have fun with the reports for Pfizer and AZ

Someone apparently vomited themselves to death after the AZ vaccine. Nasty (and NOT a definite link at this point)

Jon, Have the numbers been normalised? As it stands, I for one cannot judge the implications of the figures.

Carth 06-04-2021 17:42

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076344)
Wow, had a quick look at the 'Yellow card' reporting for the COVID vaccines. It seems a LOT of people report side effects!

The problem also exists that if you give people a list of side effects they MAY experience, coupled with a website to report them at, you'll get quite a few that think they're doing the right thing by reporting something trivial that they forget they've had on numerous occasions before. ;)

Not saying there aren't problems, but . . .

jfman 06-04-2021 18:17

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076308)
How quickly will AstraZeneca become a Swedish company if the vaccine is restricted. Much like Andy Murray is Scottish when he loses and British when he wins

I stand corrected.

Twitter informs me The Guardian have already moved from “the Oxford vaccine” to “the AstraZeneca vaccine” for bad news stories. :D

1andrew1 06-04-2021 19:58

Re: Coronavirus
 
Oxford-AstraZeneca child trial placed on hold
Quote:

A trial of the Oxford-AstraZeneca Covid vaccine on children has stopped giving out jabs while the UK's medicines regulator investigates a possible link with rare blood clots in adults.

Prof Andrew Pollard from the University of Oxford told the BBC there were no safety concerns with the trial itself, but its scientists were waiting for further information.
https://www.bbc.co.uk/news/health-56656356

Carth 06-04-2021 21:31

Re: Coronavirus
 
Does all this mean that instead of having a vaccination passport to fly abroad, you now have to prove you haven't been vaccinated instead?

Can't be having the problem of blood clots when you're flying around, especially if you're a little on the tall side ;)

jonbxx 07-04-2021 09:16

Re: Coronavirus
 
Quote:

Originally Posted by Sephiroth (Post 36076345)
Jon, Have the numbers been normalised? As it stands, I for one cannot judge the implications of the figures.

Nope, that's raw data. Yellow Card reporting is unfiltered as anyone can drop in a report here. I remember some time back when you were discussing flu vaccine side effects and I recommended dropping a Yellow Card report in.

Here are the words from the MHRA with the important bits highlighted;

Quote:

Part of our monitoring role includes reviewing reports of suspected side effects. Any member of the public or health professional can submit suspected side effects through the Yellow Card scheme. The nature of Yellow Card reporting means that reported events are not always proven side effects. Some events may have happened anyway, regardless of vaccination. This is particularly the case when millions of people are vaccinated, and especially when most vaccines are being given to the most elderly people and people who have underlying illness.
Just idly scrolling through the Pfizer list and there are some good ones in there. People reported the following as vaccine side effects;
  • 6 electric shocks
  • 1 crushed face
  • 3 sunburn cases
  • 39 negative COVID tests (oh no!)
  • 1 bitten tongue
  • 1 case of laziness
  • 1 case of low income and 1 case of high income

We want to encourage side effect reporting, even for issues that wouldn't result in a doctor or hospital visit but some of the side effects reported are a stretch!

Chris 07-04-2021 09:23

Re: Coronavirus
 
I think our society lost something when we stopped recording things like “simpleton” on the national census.

Maggy 07-04-2021 09:38

Re: Coronavirus
 
Or cretin.

Jaymoss 07-04-2021 10:15

Re: Coronavirus
 
yeah lets go back to when then hung thieves and debtors too

joglynne 07-04-2021 11:02

Re: Coronavirus
 
Quote:

Coronavirus LIVE updates as Moderna vaccine rollout begins in UK and AstraZeneca children's trial paused

The third vaccine approved for use in the UK has begun its rollout today (Wednesday).

People in Wales will begin to receive the Moderna vaccine, starting at West Wales General Hospital in Carmarthen.

The UK has bought 17 million doses of that vaccine – enough for 8.5 million people - and it has been hailed as 'another key milestone' in the fight against coronavirus.

snip ... It comes as a trial of the Oxford/AstraZeneca vaccine in children has been paused while regulators investigate reports of a rare form of blood clot among adults.

Regulators at the Medicines and Healthcare products Regulatory Agency (MHRA) are investigating a potential association between the jab and a rare form of blood clot.

A spokesperson from the university said in a statement: "Whilst there are no safety concerns in the paediatric clinical trial, we await additional information from the MHRA on its review of rare cases of thrombosis/thrombocytopaenia that have been reported in adults, before giving any further vaccinations in the trial.

"Parents and children should continue to attend all scheduled visits and can contact the trial sites if they have any questions."
https://www.manchestereveningnews.co...1-6a3f1dc60640

Sephiroth 07-04-2021 12:08

Re: Coronavirus
 
Quote:

Originally Posted by Jaymoss (Post 36076363)
yeah lets go back to when then hung thieves and debtors too

What about vaccinated persistent Remainers?

Jaymoss 07-04-2021 12:11

Re: Coronavirus
 
Quote:

Originally Posted by Sephiroth (Post 36076367)
What about vaccinated persistent Remainers?

Can not go back to it because they never hung em (unfortunately for the remoaners)

1andrew1 07-04-2021 12:20

Re: Coronavirus
 
Quote:

Originally Posted by Sephiroth (Post 36076367)
What about vaccinated persistent Remainers?

Well, I can think of one such person who ticks that box and will undoubtedly be given a Knighthood for helping save Leavers and Remainers alike from Coronavirus.

Pierre 07-04-2021 15:20

Re: Coronavirus
 
So as of last week, 130 or so cases of blood clotting side affects, after 30 odd million doses.

So potentially 4 in a 1,000,000 may develop an issue?

No need to panic then, but they will.

jfman 07-04-2021 16:03

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076384)
So as of last week, 130 or so cases of blood clotting side affects, after 30 odd million doses.

So potentially 4 in a 1,000,000 may develop an issue?

No need to panic then, but they will.

Would you vaccinate your kids?

---------- Post added at 16:03 ---------- Previous post was at 15:27 ----------

https://www.channel4.com/news/why-we...-advice-oxford

Channel 4’s story behind the story. Wonder who the ‘leading Government figure’ was and if any of today’s news would have seen the light of day if they hadn’t run with it.

1andrew1 07-04-2021 16:21

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076384)
So as of last week, 130 or so cases of blood clotting side affects, after 30 odd million doses.

So potentially 4 in a 1,000,000 may develop an issue?

No need to panic then, but they will.

The odds narrow though when you slice the data by age and gender.

Even given a chance of death of four in a million or no chance of death with another vaccine I know which one most people would choose, everything else being equal.

Carth 07-04-2021 16:36

Re: Coronavirus
 
Anyone on here ever been in a 'significant' road traffic accident?

Bet you still drive your car though . . . and take your kids with you :p:

Pierre 07-04-2021 16:46

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076385)
Would you vaccinate your kids?

No, and I'm on record on here no so long ago stating such.

There is no need. IMO, for any under 18's...........under 30's really without underlying conditions to be vaccinated, (in regards to the 18-30 unless they want to be)

1andrew1 07-04-2021 16:47

Re: Coronavirus
 
Quote:

Originally Posted by Carth (Post 36076389)
Anyone on here ever been in a 'significant' road traffic accident?

Bet you still drive your car though . . . and take your kids with you :p:

I think that comment should really be in this thread. ;)

Pierre 07-04-2021 16:48

Re: Coronavirus
 
Quote:

Originally Posted by 1andrew1 (Post 36076387)
The odds narrow though when you slice the data by age and gender.

Even given a chance of death of four in a million or no chance of death with another vaccine I know which one most people would choose, everything else being equal.

The deaths is not 4 in a million, that's cases. I believe there have still only been 7 deaths.

jonbxx 07-04-2021 16:56

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076394)
The deaths is not 4 in a million, that's cases. I believe there have still only been 7 deaths.

A few more - 19 deaths according to the MHRA.

We still want under 30s vaccinated by the way if we want herd immunity...

Pierre 07-04-2021 17:09

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076395)
A few more - 19 deaths according to the MHRA.

We still want under 30s vaccinated by the way if we want herd immunity...

I'm not bothered about "herd immunity", as long as "at risk" groups are protected, hospitalisations are minimised to not over-burden the NHS and deaths are also greatly reduced. That's good enough.

Vaccinations should be a matter of choice, that's why I'm also against passports (domestic) and other means to coerce people.

And there is Zero evidence that kids need to be vaccinated.

19 deaths out of 30million doses..1 death per 1.5 million.

Hugh 07-04-2021 17:12

Re: Coronavirus
 
The more unvaccinated people who catch it and spread it (no matter what age they are), the more mutations will occur which the current vaccines may not work against.

Evidence shows that teenagers, particularly older teens, catch and spread it as much as adults.

Pierre 07-04-2021 17:14

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36076398)
The more unvaccinated people who catch it and spread it (no matter what age they are), the more mutations will occur which the current vaccines may not work against.

which is what happens every year with the flu.

It has already been acknowledged that we will have to be vaccinated annually, as we do with the flu.

Still no way I would force anyone to be vaccinated that did not want to be, or coerce anybody by denying them access to freedoms if they haven't.

Quote:

Evidence shows that teenagers, particularly older teens, catch and spread it as much as adults.
So what? if you've been vaccinated.

Chris 07-04-2021 17:25

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076313)
I don't think there's any doubt about the fact there's an identifiable risk given it's independently noted in the UK, Germany and others.

The question is whether it's an acceptable risk, which for a vaccination programme by consent hits problems for the members of the public who have been told they are extremely low risk of Covid complications anyway.

Per the latest announcements from the MHRA, EMA and WHO, there is a noted association but still no demonstrated causal link.

https://www.bbc.co.uk/news/world-europe-56665150

There is, by definition, still doubt over whether there is an “identifiable risk” with the Oxford-AZ vaccine. A link is plausible and there are plausible hypotheses around causation.

But as I’m sure you’ll agree, it’s important to be led by the science and not state more or less than has been established.

Hugh 07-04-2021 17:27

Re: Coronavirus
 
Quote:

Originally Posted by Carth (Post 36076389)
Anyone on here ever been in a 'significant' road traffic accident?

Bet you still drive your car though . . . and take your kids with you :p:

But if I knew that the significant road accident could then cause a number of other road accidents, who would then go on to cause lots more road accidents, which would then go on to cause even greater numbers of road accidents - I probably wouldn't... :erm:

---------- Post added at 17:27 ---------- Previous post was at 17:26 ----------

Quote:

Originally Posted by Pierre (Post 36076399)
which is what happens every year with the flu.

It has already been acknowledged that we will have to be vaccinated annually, as we do with the flu.

Still no way I would force anyone to be vaccinated that did not want to be, or coerce anybody by denying them access to freedoms if they haven't.



So what? if you've been vaccinated.

But, and I can't repeat this often enough, it isn't the flu...

And if one of the mutations finds a way round the vaccine, that defeats all the work we have put in already.

pip08456 07-04-2021 17:50

Re: Coronavirus
 
New advice issued by MHRA re AZ and blood clots.

https://www.gov.uk/government/news/m...ur-blood-clots

jfman 07-04-2021 17:56

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076392)
No, and I'm on record on here no so long ago stating such.

There is no need. IMO, for any under 18's...........under 30's really without underlying conditions to be vaccinated, (in regards to the 18-30 unless they want to be)

Without a vaccination programme (and confidence in it) in practice the herd immunity threshold will never be hit without significant vaccine penetration (or infection) within those groups.

More restrictions, for longer and potentially future lockdowns.

TheDaddy 07-04-2021 17:56

Re: Coronavirus
 
Quote:

Originally Posted by Jaymoss (Post 36076368)
Can not go back to it because they never hung em (unfortunately for the remoaners)

Just hung out to dry...

Quote:

Originally Posted by Hugh (Post 36076402)

And if one of the mutations finds a way round the vaccine, that defeats all the work we have put in already.

And that's the point I was making the other day about France but lost the will to proceed due to people knowing better :rolleyes:

jfman 07-04-2021 17:59

Re: Coronavirus
 
Quote:

Originally Posted by Chris (Post 36076401)
Per the latest announcements from the MHRA, EMA and WHO, there is a noted association but still no demonstrated causal link.

https://www.bbc.co.uk/news/world-europe-56665150

There is, by definition, still doubt over whether there is an “identifiable risk” with the Oxford-AZ vaccine. A link is plausible and there are plausible hypotheses around causation.

But as I’m sure you’ll agree, it’s important to be led by the science and not state more or less than has been established.

Suspect the politicians in the UK and EU - who don't have a vaccination plan of any substance without significant proportions of AZ vaccine will always play these 'doubts' despite the science.

The important part is that the benefits outweigh the risks, which they do. But that's not to say there are no risks.

What is quite obvious is that despite a huge "rally behind the flag' effort this couldn't be hushed up any longer against emerging evidence.

Pierre 07-04-2021 18:24

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36076402)
But, and I can't repeat this often enough, it isn't the flu...

I know it isn’t but it will be monitored and managed annually like the flu

Quote:

And if one of the mutations finds a way round the vaccine, that defeats all the work we have put in already.
No evidence of that, the vaccine producers have already gone on record that they can adapt and develop the vaccines to address other strains as and when they might appear.

---------- Post added at 18:24 ---------- Previous post was at 18:21 ----------

Quote:

Originally Posted by jfman (Post 36076406)
Without a vaccination programme (and confidence in it) in practice the herd immunity threshold will never be hit without significant vaccine penetration (or infection) within those groups.

More restrictions, for longer and potentially future lockdowns.

If you are vaccinating those that need to be vaccinated, why the need for “herd immunity”. Zero COVID is like chasing the end of the rainbow.

Vaccinate the vulnerable, manage the risks, live our lives.

jfman 07-04-2021 18:25

Re: Coronavirus
 
Nobody is disputing the skill of vaccine developers. The capability to manufacture and distribute vaccines on the other hand takes months. Months of lockdowns and other restrictions.

pip08456 07-04-2021 18:26

Re: Coronavirus
 
Quote:

Under 30s in the UK will be offered the Pfizer or Moderna vaccine instead of AstraZeneca due to a small number of blood clots
"Changes in preference for vaccines are business as usual, and this is a course correction" - Jonathan Van Tam

Chris 07-04-2021 18:27

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076408)
What is quite obvious is that despite a huge "rally behind the flag' effort this couldn't be hushed up any longer against emerging evidence.

Yes, I'm sure the EMA was absolutely at the beck and call of No.10 when it came to announcing findings over this.

jfman 07-04-2021 18:32

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076411)
If you are vaccinating those that need to be vaccinated, why the need for “herd immunity”. Zero COVID is like chasing the end of the rainbow.

Vaccinate the vulnerable, manage the risks, live our lives.

Herd immunity and zero Covid aren’t one and the same thing.

Managing the risk is to remove as many opportunities for the virus to mutate as possible.

Not managing that risk - not reaching the herd immunity threshold - is resigning ourselves to failure. Inevitable mutation, more restrictions, more lockdowns, greater economic costs and more requirement for vaccines in the long run.

---------- Post added at 18:32 ---------- Previous post was at 18:29 ----------

Quote:

Originally Posted by Chris (Post 36076415)
Yes, I'm sure the EMA was absolutely at the beck and call of No.10 when it came to announcing findings over this.

Nobody is doubting the EMAs transparency given they identified the risks first despite a slower vaccine rollout. We passed the threshold at which is was possible to blame it as the EU deflecting.

It’s apparent we’ve known for some time. The Telegraph article describing an upcoming “difficult two weeks” for the Oxford vaccine didn’t spawn itself into existence. Someone briefed that.

Hugh 07-04-2021 18:59

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076411)
I know it isn’t but it will be monitored and managed annually like the flu



No evidence of that, the vaccine producers have already gone on record that they can adapt and develop the vaccines to address other strains as and when they might appear.

---------- Post added at 18:24 ---------- Previous post was at 18:21 ----------



If you are vaccinating those that need to be vaccinated, why the need for “herd immunity”. Zero COVID is like chasing the end of the rainbow.

Vaccinate the vulnerable, manage the risks, live our lives.

Not sure I think "monitoring and managing" something with six times the death rate of flu an appropriate method of health management...

COVID is much more infectious and deadlier than the flu,so it can’t be "managed and monitored" like it.

https://www.health.org.uk/publicatio...a-proved-wrong

Quote:

Key points

Myth 1: ‘Those who die from COVID-19 would have died soon anyway’

In the first year of COVID-19 (5 March 2020 to 5 March 2021), 1.5 million potential years of life were lost in the UK as a result of people dying with the virus. In England and Wales alone this figure is 1.4 million.
On average, each of the 146,000 people who died with COVID-19 lost 10.2 years of life.
Myth 2: ‘It’s just a bad flu season’

In a bad flu year on average around 30,000 people in the UK die from flu and pneumonia, with a loss of around 250,000 life years. This is a sixth of the life years lost to COVID-19.

We have more detailed data for England and Wales. This shows us that, even looking only at those aged older than 75 (who account for most COVID-19 and flu deaths) – COVID-19 has been much more deadly. In 2018, a bad flu year, around 25,000 people older than 75 died from flu or pneumonia. These people lost a total of 140,000 years of life – 5.75 years each on average. This is about a quarter of the life years lost among those older than 75 from COVID-19.

More years of men's lives have been lost in the pandemic than women’s. Again, looking at England and Wales, women older than 75 lost around four-times more years of life than for a bad flu season; for men it was five times higher.
Myth 3: ‘COVID-19 is the great leveller – we are all equally at risk’

COVID-19 was not the great leveller. People in the 20% most deprived parts of England were twice as likely to die from COVID-19 as those in the least deprived areas. They also died at younger ages, so may have lost more years of life. While existing health inequalities mean these people may have had lower life expectancy, the analysis found that in total, 35% more lives were lost in the 20% most deprived areas than the least, with 45% more years of life lost in total.
On average, each person who died in the most deprived quintile lost 11 years of their life, compared with 10 years in the least deprived.

pip08456 07-04-2021 19:00

Re: Coronavirus
 
Quote:

Originally Posted by Chris (Post 36076415)
Yes, I'm sure the EMA was absolutely at the beck and call of No.10 when it came to announcing findings over this.

The EMA have announced their findiings today.

Quote:

EMA confirms overall benefit-risk remains positive

EMA’s safety committee (PRAC) has concluded today that unusual blood clots with low blood platelets should be listed as very rare side effects of Vaxzevria (formerly COVID-19 Vaccine AstraZeneca).

In reaching its conclusion, the committee took into consideration all currently available evidence, including the advice from an ad hoc expert group.
https://www.ema.europa.eu/en/news/as...lots-low-blood

papa smurf 07-04-2021 19:04

Re: Coronavirus
 
No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty


Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.


https://www.cityam.com/no-more-lockd...-chris-whitty/

pip08456 07-04-2021 19:10

Re: Coronavirus
 
Quote:

Originally Posted by papa smurf (Post 36076424)
No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty


Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.


https://www.cityam.com/no-more-lockd...-chris-whitty/

If that is the case then no need for (internal) covid vaccine passport or twice a week testing.

papa smurf 07-04-2021 19:12

Re: Coronavirus
 
Quote:

Originally Posted by pip08456 (Post 36076426)
If that is the case then no need for (internal) covid vaccine passport or twice a week testing.

we just may have to admit it's over and start living and working again.

jfman 07-04-2021 19:20

Re: Coronavirus
 
Quote:

Originally Posted by pip08456 (Post 36076426)
If that is the case then no need for (internal) covid vaccine passport or twice a week testing.

On the contrary - it makes them more essential to managing the response. Not less.

Pierre 07-04-2021 19:50

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36076422)
Not sure I think "monitoring and managing" something with six times the death rate of flu an appropriate method of health management...

Well..................that’s why you will be vaccinated every year.......Like........the........flu

Quote:

Jesse Bloom, an evolutionary biologist at the Fred Hutchinson Cancer Research Center in Seattle, thinks the coronavirus might follow a similar path. “I do think SARS-CoV-2 will become a less serious problem and something like flu,” he says. Shaman and others say the virus could also settle into a seasonal pattern of annual winter outbreaks similar to flu.
https://www.nature.com/articles/d41586-021-00396-2

Quote:

"And this starts to look more like annual flu than anything else and that may be the direction we end up going." - Patrick Vallance
https://www.smh.com.au/world/europe/...20-p566no.html

Quote:

But even if the virus sticks around, new vaccines and new drugs to fight the virus mean it's unlikely to cause severe illness in the future. Offit predicts "that eventually, it will cause fewer deaths than influenza."

It is possible, experts say, that COVID-19 could become a seasonal illness, like the flu. Virologists call this an "endemic" disease -- one that is constantly circulating among us. In the years and decades to come, many people will be exposed to it in childhood and develop some immunity, which would protect them later in life against serious disease.
https://abcnews.go.com/Health/covid-...ry?id=75830451

Quote:

"Variations of this virus will be around for a long time," Langlois said in an interview airing today on CBC's political affairs program The House.

"It may even become endemic, which means that every year when we get our flu shot, we'll be getting our coronavirus shot for whatever variants are circulating at that specific time."
https://www.cbc.ca/radio/thehouse/co...ants-1.5973320

---------- Post added at 19:48 ---------- Previous post was at 19:46 ----------

Quote:

Originally Posted by papa smurf (Post 36076424)
No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty


Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.


https://www.cityam.com/no-more-lockd...-chris-whitty/

Don’t tell that to Hugh!

---------- Post added at 19:50 ---------- Previous post was at 19:48 ----------

Quote:

Originally Posted by jfman (Post 36076429)
On the contrary - it makes them more essential to managing the response. Not less.

No it doesn’t. The response is “vaccinate all those required - annually”

nomadking 07-04-2021 20:17

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076314)
Pretty much this - if there is a small risk of increased clotting events in certain populations and there are enough vaccines of different types to go around, then recommending AZ for those at a lower risk and Pfizer, Janssen, Moderna and Novavax for everyone else seems sensible.

That said, if you're in an 'at risk' group for clotting events and already have had your first shot of AZ, not sure what's going to happen there - mix and match or take the risk of a second shot of AZ?

They're likely to already be on blood thinners such as Warfarin or Rivaroxaban to protect against such events.

pip08456 07-04-2021 20:21

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076429)
On the contrary - it makes them more essential to managing the response. Not less.

And that is to manage the response to what?

Quote:

Lead author Jon Deeks, professor of biostatistics at the University of Birmingham, said: "These tests work a lot less well in people who are asymptomatic than symptomatic. The government has not been clear on this.

"The only data we have is based on the [Liverpool and Birmingham] studies, where a total of 78 people had COVID-19, when 40 million tests have been given out.

"I personally find it quite shocking that the government thinks this is an adequate evidence base on which to base such a large, expensive, and quite invasive policy."
https://news.sky.com/story/covid-19-...place-12266517

There's also this.

Quote:

Richard Tedder, senior research investigator in medical virology at Imperial College London, commented, “This assay is simply not sensitive enough to use to test persons with a view to confirming an absence of infection and thereby an absence of infectivity. A negative result with this lateral flow test simply does not infer an absence of infection.”

The findings contrast with an earlier assessment of the Innova test by Public Health England’s Porton Down laboratory and the University of Oxford, which found an overall sensitivity of 76.8% but showed that sensitivity dropped to 58% when carried out by self-trained staff at a Boots track-and-trace centre.
https://www.bmj.com/content/371/bmj.m4848

jfman 07-04-2021 20:59

Re: Coronavirus
 
Manage the response to the Covid 19 pandemic. The same as always.

Pierre says zero Covid is an unachievable ambition. However there is no “living with the virus” in the short term. The idea that we hit a magic number of vaccinations and the Government just open the floodgates and say “we did all we could do” continues to be fanciful.

As I’ve said consistently throughout the thread the decision making that led to lockdown 1 makes another one inevitable unless something significant changes.

The vaccine should be a game changer. However the basics will still apply for some time - finding cases, identifying contacts, identifying who is at risk among those contacts. This should be much easier with the vaccines reducing transmission.

There’s still a significant amount of unknowns. Vaccine performance against known variants, vaccine performance against as yet unknown variants, vaccine performance over time.

Complacency now risks making all the same mistakes all over again and undoing significant achievements to date.

Then again. Some people haven’t considered Covid that serious for 15 months so I’m unsurprised some haven’t grasped this either.

Hugh 07-04-2021 21:18

Re: Coronavirus
 
Quote:

Originally Posted by papa smurf (Post 36076424)
No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty


Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.

https://www.cityam.com/no-more-lockd...-chris-whitty/

As I replied, when you posted the same link 3 days ago, the full message he said was...

Quote:

Originally Posted by papa smurf View Post
No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty

Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.

England’s chief medical officer said the UK would have to learn to live with the virus, noting that up to 25,000 people can die in a bad flu year without the figure hitting the headlines.

https://www.cityam.com/no-more-lockd...-chris-whitty/
https://news.sky.com/story/covid-19-...iants-12263319

Quote:

Quote:
COVID-19: Chris Whitty warns virus measures needed for another two years to combat threat of variants

Professor Whitty says a "period of risk" remains until there is a bank of vaccines that work against coronavirus variants.

Coronavirus safety measures are likely to still be necessary for another two years, England's chief medical officer has said.

Professor Chris Whitty said it could take up to two years for the world to build up a bank of vaccines and technologies capable of rapidly dealing with COVID-19 variants and outbreaks.

While he said these tools will eventually "find a way through", there still remains a level of risk that needs to be managed before then.

Speaking during a Royal Society of Medicine webinar on Thursday, Professor Whitty said a cautious approach will be needed for the next couple of years "because we've got such a difficult situation to go through at the moment".

He added: "What we don't want to be is in a situation where we look back in six months and say 'If we'd only just been a bit more cautious for a month or two we would've actually got through [vaccinating] the whole population, we'd have understood a lot more, we'd know how to deal with this, we'd probably have a few variant vaccines on the stocks'.

"I don't think though this should be seen as an indefinite posture, I think this is a matter of probably the next year or two whilst we understand how to do this and find a way of responding rapidly to variants."

However, he said a "very wide portfolio of vaccines" is likely to be available in around two years, offering greater protection.

Pierre 07-04-2021 21:52

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36076447)
As I replied, when you posted the same link 3 days ago, the full message he said was...


https://news.sky.com/story/covid-19-...iants-12263319

Don’t worry Papa , you can always bank this and post in a years time if Hugh has got it wrong.......he’d appreciate that.

jfman 07-04-2021 21:52

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076448)
Don’t worry Papa , you can always bank this and post in a years time if Hugh has got it wrong.......he’d appreciate that.

Just as well I stopped banking yours.

papa smurf 07-04-2021 21:55

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076448)
Don’t worry Papa , you can always bank this and post in a years time if Hugh has got it wrong.......he’d appreciate that.

In the meantime we can just treat it as we do a seasonal flue....

daveeb 07-04-2021 22:08

Re: Coronavirus
 
Quote:

Originally Posted by papa smurf (Post 36076450)
In the meantime we can just treat it as we do a seasonal flue....

You mean get a chimney sweep to sort it out? :erm:

Pierre 07-04-2021 22:26

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076449)
Just as well I stopped banking yours.

Likewise.

1andrew1 07-04-2021 23:08

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076452)
Likewise.

A thread without jfman-Pierre discussion is like a house without windows. :D

Chris 07-04-2021 23:23

Re: Coronavirus
 
And with that, can we get back to the topic please.

jfman 07-04-2021 23:25

Re: Coronavirus
 
Iain “get back to the office and buy a coffee you plebs” Duncan-Smith isn’t happy about the MHRA advice.

https://www.theguardian.com/world/20...ers-say-tories

That’s good enough for me. If we can get a quote from Steve Baker of the (I presume ironically named) Covid recovery group I’ll sleep easy tonight.

Chris 07-04-2021 23:31

Re: Coronavirus
 
He doesn’t understand what they thought they were doing ... well, they were doing exactly what they do with every drug that starts to produce post-marketing data. The only problem is that in this case there’s extreme scrutiny of the whole process, which is understandable and unavoidable under the circumstances. The only slightly different line they could have taken would be to advise alternative vaccines without actually acknowledging that there’s a likely risk factor with the Ox-AZ vaccine but again, given the level of scrutiny this whole process is under, that probably wouldn’t have flown - it would just have looked like a fudge, which of course it would have been.

Jonathan Van Tam’s presentation this afternoon was erudite, balanced and very reassuring.

1andrew1 07-04-2021 23:32

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076458)
Iain “get back to the office and buy a coffee you plebs” Duncan-Smith isn’t happy about the MHRA advice.

https://www.theguardian.com/world/20...ers-say-tories

That’s good enough for me.

I'm not sure the MHRA could have said anything else. Unfortunately, whilst IDS may yearn for a simple life, the MHRA has to follow the science.

jfman 07-04-2021 23:45

Re: Coronavirus
 
Steve Baker is out retweeting folk scaremongering about vaccinating kids.

That’s reassuring that our Conservative backbench MPs have the health of the nation at heart. Remember, as always, there’s no economic recovery without solving the health issue. ONS data shows kids driving all but the first wave (data not available), and no doubt the next one too as schools return with pitiful non-pharmaceutical interventions.

---------- Post added at 23:45 ---------- Previous post was at 23:37 ----------

Quote:

Originally Posted by 1andrew1 (Post 36076460)
I'm not sure the MHRA could have said anything else. Unfortunately, whilst IDS may yearn for a simple life, the MHRA has to follow the science.

Once the European data became so compelling the game was up. No amount of selective interpretation or skewing the data was ever going to allow the charade to continue.

It’s laughable really to think so-called credible scientists peddled the line a mere few weeks ago that there were less of these rare types of clots among those vaccinated than would be expected to be seen in a population of similar size. Including a release on the MHRA website that lasted a mere two days before being taken down.

The timeline can be traced from 15 March to the Telegraph article on 30 March. At some point between those dates the 15 March statements became demonstrably false to such a clear extent the story was put out on that basis.

Pierre 08-04-2021 00:10

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076461)
Steve Baker is out retweeting folk scaremongering about vaccinating kids.

That’s reassuring that our Conservative backbench MPs have the health of the nation at heart. Remember, as always, there’s no economic recovery without solving the health issue. ONS data shows kids driving all but the first wave (data not available), and no doubt the next one too as schools return with pitiful non-pharmaceutical interventions.

---------- Post added at 23:45 ---------- Previous post was at 23:37 ----------



Once the European data became so compelling the game was up. No amount of selective interpretation or skewing the data was ever going to allow the charade to continue.

It’s laughable really to think so-called credible scientists peddled the line a mere few weeks ago that there were less of these rare types of clots among those vaccinated than would be expected to be seen in a population of similar size. Including a release on the MHRA website that lasted a mere two days before being taken down.

The timeline can be traced from 15 March to the Telegraph article on 30 March. At some point between those dates the 15 March statements became demonstrably false to such a clear extent the story was put out on that basis.

Usually there would be substance in your posts that I could break down and argue against, or for and drive the debate forward.

There is nothing in that diatribe above, nothing.

jfman 08-04-2021 00:19

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36076466)
Usually there would be substance in your posts that I could break down and argue against, or for and drive the debate forward.

There is nothing in that diatribe above, nothing.

Now, now Pierre. Your inability to argue a counterpoint isn’t something to be ashamed of but unsurprising given the link you posted the other day about it being a conspiracy against AZ because it’s the cheap vaccine. Politicians meddling over science was the claim. Ironically it appears our politicians been doing that all along, including a plea to suppress the Channel 4 story.

I like the fact IDS loves freedom that much, opposing vaccine passports, he doesn’t want the population to have informed consent when taking the vaccine. The contradiction is hilarious really. Unsurprising, but hilarious.

Carth 08-04-2021 01:51

Re: Coronavirus
 
All this, yet still many people think the 'experts' are right every time . . . about everything ;)

Pierre 08-04-2021 09:05

Re: Coronavirus
 
OK then

Quote:

Originally Posted by jfman (Post 36076461)
Steve Baker is out retweeting folk scaremongering about vaccinating ONS data shows kids driving all but the first wave (data not available), and no doubt the next one too as schools return with pitiful non-pharmaceutical interventions.

But

Quote:

But staff, parents and pupils can feel reassured by current evidence that shows transmission of COVID-19 in schools remains low.
And

Quote:

infection rates among primary school staff and students was extremely low (less than 5%).
What about

Quote:

The study involved asymptomatic testing of 10,000 students and staff across England and despite a slight over-representation in areas with higher infection rates, the study showed that infection rates in schools were low.
https://publichealthmatters.blog.gov...id-in-schools/

Again, once everybody that needs to be vaccinated has been vaccinated we should just get on. Under 18’s being vaccinated will be at the discretion of the parents.

Being vaccinated should be/is a matter of personal choice.

Nobody should be discriminated against for not having the vaccine.

If we stick to those four principles, i don’t see what the issue would be

jonbxx 08-04-2021 09:21

Re: Coronavirus
 
Back on the blood clotting risk thing, I found this paper from the Winton Centre for Risk and Evidence Communication at Cambridge University which is a very good discussion of the risks and benefits for the AZ vaccine in different age groups depending on the prevalence of COVID infections in the population.

The top figure is the standout one. At current infection rates, the risk of blood clots of the type seen in vaccinated patients in the 20-29 year age range is higher than the risk of ICU admission due to COVID.

If infection rates rise, then the risk/benefit swings towards vaccination but of course we want to go towards lower rates...

jfman 08-04-2021 09:27

Re: Coronavirus
 
With the best will in the world Pierre you're making the same false assumptions as the herd immunity crowd last March.

Transmission in schools remains low while community prevalence is low. It's inevitable that infection, given time without mitigation, will spread and infect significant proportions of the school age population and into the wider population - among those unvaccinated and where vaccine efficacy has waned.

It's then an absolute inevitability that at a later date we will be spending more time, money and effort in lockdowns against an escape variant.

I agree being vaccinated should be a matter of choice. However if too many people choose not to the herd immunity threshold is never hit and we spend years firefighting.

If we say it's not safe to vaccinate teenagers and those younger why would someone in their early 20s volunteer to take it? Suddenly HIT requires almost 100% uptake of a 90% vaccine - something we've not seen against new variants.

If we get 70% uptake of a 70% vaccine then mutant variants are an absolute inevitability.

Vaccinate the vulnerable is 2021s 'shield the vulnerable'. While it's rational to want HIT to be achieved by other people taking the vaccine - personal risk becomes zero - the problem is where everyone chooses to be rational at an individual level.

---------- Post added at 09:27 ---------- Previous post was at 09:23 ----------

Quote:

Originally Posted by jonbxx (Post 36076480)
Back on the blood clotting risk thing, I found this paper from the Winton Centre for Risk and Evidence Communication at Cambridge University which is a very good discussion of the risks and benefits for the AZ vaccine in different age groups depending on the prevalence of COVID infections in the population.

The top figure is the standout one. At current infection rates, the risk of blood clots of the type seen in vaccinated patients in the 20-29 year age range is higher than the risk of ICU admission due to COVID.

If infection rates rise, then the risk/benefit swings towards vaccination but of course we want to go towards lower rates...

So a rational individual doesn't take the vaccine but hopes everyone else does. Especially whatever politician was leaning on Channel 4 to suppress the story because it could slow easing of restrictions by a mere two weeks.

Hugh 08-04-2021 10:57

Re: Coronavirus
 
Quote:

Originally Posted by Carth (Post 36076468)
All this, yet still many people think the 'experts' are right every time . . . about everything ;)

No, they’re not - but they’re right more often about things because they base their decisions & recommendations on science & experience, and are willing to change their decisions & recommendations when new evidence comes to light.

No one is right all the time about everything - but I assume you trust your doctor’s diagnosis over some random in the street?

pip08456 08-04-2021 11:00

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076481)
With the best will in the world Pierre you're making the same false assumptions as the herd immunity crowd last March.

Transmission in schools remains low while community prevalence is low. It's inevitable that infection, given time without mitigation, will spread and infect significant proportions of the school age population and into the wider population - among those unvaccinated and where vaccine efficacy has waned.

It's then an absolute inevitability that at a later date we will be spending more time, money and effort in lockdowns against an escape variant.

I agree being vaccinated should be a matter of choice. However if too many people choose not to the herd immunity threshold is never hit and we spend years firefighting.

If we say it's not safe to vaccinate teenagers and those younger why would someone in their early 20s volunteer to take it? Suddenly HIT requires almost 100% uptake of a 90% vaccine - something we've not seen against new variants.

If we get 70% uptake of a 70% vaccine then mutant variants are an absolute inevitability.

Vaccinate the vulnerable is 2021s 'shield the vulnerable'. While it's rational to want HIT to be achieved by other people taking the vaccine - personal risk becomes zero - the problem is where everyone chooses to be rational at an individual level.

---------- Post added at 09:27 ---------- Previous post was at 09:23 ----------



So a rational individual doesn't take the vaccine but hopes everyone else does. Especially whatever politician was leaning on Channel 4 to suppress the story because it could slow easing of restrictions by a mere two weeks.

Talking of herd immunity.

Quote:

Britain will achieve herd immunity on Monday

UCL modelling says number of people with protection either through vaccination or previous infection will hit 73.4 per cent on April 12.

According to the UCL results, published this week, the number of people who have protection against the virus either through vaccination or previous infection will hit 73.4 per cent on April 12 – enough to tip the country into herd immunity.

The number is in stark contrast to the modelling released by Imperial College this week, which suggested there was just 34 per cent protection by the end of March.
https://www.telegraph.co.uk/news/202...eshold-monday/

jonbxx 08-04-2021 11:03

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076481)
With the best will in the world Pierre you're making the same false assumptions as the herd immunity crowd last March.

Transmission in schools remains low while community prevalence is low. It's inevitable that infection, given time without mitigation, will spread and infect significant proportions of the school age population and into the wider population - among those unvaccinated and where vaccine efficacy has waned.

It's then an absolute inevitability that at a later date we will be spending more time, money and effort in lockdowns against an escape variant.

I agree being vaccinated should be a matter of choice. However if too many people choose not to the herd immunity threshold is never hit and we spend years firefighting.

If we say it's not safe to vaccinate teenagers and those younger why would someone in their early 20s volunteer to take it? Suddenly HIT requires almost 100% uptake of a 90% vaccine - something we've not seen against new variants.

If we get 70% uptake of a 70% vaccine then mutant variants are an absolute inevitability.

Vaccinate the vulnerable is 2021s 'shield the vulnerable'. While it's rational to want HIT to be achieved by other people taking the vaccine - personal risk becomes zero - the problem is where everyone chooses to be rational at an individual level.

---------- Post added at 09:27 ---------- Previous post was at 09:23 ----------



So a rational individual doesn't take the vaccine but hopes everyone else does. Especially whatever politician was leaning on Channel 4 to suppress the story because it could slow easing of restrictions by a mere two weeks.

Yeah, this is where health messaging becomes difficult and can also be an illuminating window into the British pysche. If we look back at the start of this whole thing, the messaging was 'protect the NHS'. The NHS polls well in this country as most people are proud of the NHS as a British institution. Eventually though, messaging gets old and things change and went from protecting the NHS to a more fearful message. What is interesting however is the fearful message wasn't out ward looking - 'behave yourselves or you will kill someone's nan' but more a 'you really don't want to get COVID'.

Masks are a great example of this. The evidence of masks protecting the user is low but the evidence of masks protecting other is much stronger. This was picked up by anti mask people early on as evidence masks don't work which is somewhat true but only for the person wearing them. Mask wearing protects others. So why isn't mask wearing pitched as a civic duty? Do the people putting together the messaging think that we wouldn't care about protecting others or do they know that we wouldn't care about protecting others? The best case scenario is the first but I fear it is the second.

This is where we get to vaccines. The absolute necessity of vaccines for the protection 18-30 years olds is probably low (again, long COVID excepted) but, as jfman said, we need to get the uptake up for herd immunity or at least to lower the Re value. Matt Hancock said this morning on the BBC that is was your 'patriotic duty' to be vaccinated which is arguable (in that I don't want to argue about this!) but it is definitely a civic duty for younger people to be vaccinated to help protect the older population who either didn't seroconvert or couldn't be jabbed.

We tend to get more right wing as we age. Left wing politics is more around collective responsibility in contrast with more personal responsibility on the right side of things. Should we be pitching vaccination as a duty to society when the time comes for younger people to get jabbed?

Carth 08-04-2021 11:20

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36076490)
No, they’re not - but they’re right more often about things because they base their decisions & recommendations on science & experience, and are willing to change their decisions & recommendations when new evidence comes to light.

No one is right all the time about everything - but I assume you trust your doctor’s diagnosis over some random in the street/

Actually no I don't. All my doctor wants to do is prescribe me numerous tablets based on the rather shady 5 minute 'telephone consultation' that is the norm nowadays. I haven't seen a doctor in a year - in fact I'm close to telling the practice to get stuffed and simply use the hospital casualty dept. instead :rolleyes:

I guess you could also call me an expert in 'not believing everything an expert says', although I've never published any papers on it ;)

spiderplant 08-04-2021 11:41

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076481)
So a rational individual doesn't take the vaccine but hopes everyone else does.

Only in the absence of other vaccines. Ideally you'd get non-AZ, and not care what everyone else gets as long as they get one.

Just wondering: Are all three approved vaccines still considered 100% effective against serious illness? If not, any difference probably outweighs the blood clot risk.

Quote:

Originally Posted by Telegraph
Britain will achieve herd immunity on Monday

How convenient!

jfman 08-04-2021 11:51

Re: Coronavirus
 
Quote:

Originally Posted by jonbxx (Post 36076493)
Yeah, this is where health messaging becomes difficult and can also be an illuminating window into the British pysche. If we look back at the start of this whole thing, the messaging was 'protect the NHS'. The NHS polls well in this country as most people are proud of the NHS as a British institution. Eventually though, messaging gets old and things change and went from protecting the NHS to a more fearful message. What is interesting however is the fearful message wasn't out ward looking - 'behave yourselves or you will kill someone's nan' but more a 'you really don't want to get COVID'.

Masks are a great example of this. The evidence of masks protecting the user is low but the evidence of masks protecting other is much stronger. This was picked up by anti mask people early on as evidence masks don't work which is somewhat true but only for the person wearing them. Mask wearing protects others. So why isn't mask wearing pitched as a civic duty? Do the people putting together the messaging think that we wouldn't care about protecting others or do they know that we wouldn't care about protecting others? The best case scenario is the first but I fear it is the second.

This is where we get to vaccines. The absolute necessity of vaccines for the protection 18-30 years olds is probably low (again, long COVID excepted) but, as jfman said, we need to get the uptake up for herd immunity or at least to lower the Re value. Matt Hancock said this morning on the BBC that is was your 'patriotic duty' to be vaccinated which is arguable (in that I don't want to argue about this!) but it is definitely a civic duty for younger people to be vaccinated to help protect the older population who either didn't seroconvert or couldn't be jabbed.

We tend to get more right wing as we age. Left wing politics is more around collective responsibility in contrast with more personal responsibility on the right side of things. Should we be pitching vaccination as a duty to society when the time comes for younger people to get jabbed?

Or you simply change the dynamics of the question.

“What’s in it for me?”

This is where vaccine passports/certification presents a significant opportunity to shift vaccination from being ‘for the collective good’ to in someone’s personal interest. That’s why they are absolutely inevitable - to inconvenience those who want to sit back and opt out of the 70%+.

---------- Post added at 11:51 ---------- Previous post was at 11:47 ----------

Quote:

Originally Posted by spiderplant (Post 36076496)
Only in the absence of other vaccines. Ideally you'd get non-AZ, and not care what everyone else gets as long as they get one.

Just wondering: Are all three approved vaccines still considered 100% effective against serious illness? If not, any difference probably outweighs the blood clot risk.

How convenient!

You’re assuming we are being given all the information.

With political pressure from Tory backbenchers, and arguably Government itself, to prop up confidence in the vaccination drive to speed up easing restrictions the legitimate question remains would they tell us if any red flags arose?

I’d contest that the evidence from the MHRA to date suggests they would not.

Ken W 08-04-2021 14:34

Re: Coronavirus
 
My second JAB is Saturday 10th (Oxford vaccine)

Hugh 08-04-2021 14:39

Re: Coronavirus
 
Quote:

Originally Posted by spiderplant (Post 36076496)
Only in the absence of other vaccines. Ideally you'd get non-AZ, and not care what everyone else gets as long as they get one.

Just wondering: Are all three approved vaccines still considered 100% effective against serious illness? If not, any difference probably outweighs the blood clot risk.

Quote:

Originally Posted by Telegraph
Britain will achieve herd immunity on Monday
How convenient!

Source material for the herd immunity claim - lots of caveats...

Quote:

Much like long-term weather forecasts, the ensuing predictions should not be taken too seriously because there is an inherent (although quantified) uncertainty about underlying epidemiological and socio-behavioural variables.
Quote:

The current estimates of the herd immunity threshold show that it has risen substantially since last July and is predicted to fall again during the spring. Clearly, there is a substantial amount of uncertainty about these long-term forecasts — as indicated by the wide credible intervals. Part of this uncertainty is due to the fluctuations in transmission risk and mobility.
https://www.fil.ion.ucl.ac.uk/spm/co...ing_040421.pdf

---------- Post added at 14:39 ---------- Previous post was at 14:37 ----------

Quote:

Originally Posted by Carth (Post 36076495)
Actually no I don't. All my doctor wants to do is prescribe me numerous tablets based on the rather shady 5 minute 'telephone consultation' that is the norm nowadays. I haven't seen a doctor in a year - in fact I'm close to telling the practice to get stuffed and simply use the hospital casualty dept. instead :rolleyes:

I guess you could also call me an expert in 'not believing everything an expert says', although I've never published any papers on it ;)

Sorry to hear you’ve got a duff medic - never good.

Can’t you change doctor/practice?

jonbxx 08-04-2021 15:20

Re: Coronavirus
 
Quote:

Originally Posted by jfman (Post 36076497)
Or you simply change the dynamics of the question.

“What’s in it for me?”

This is where vaccine passports/certification presents a significant opportunity to shift vaccination from being ‘for the collective good’ to in someone’s personal interest. That’s why they are absolutely inevitable - to inconvenience those who want to sit back and opt out of the 70%+.

Time unleash the Nuffield Intervention Ladder :tu: By my reckoning, we're half up the ladder at 'Guide choice by changing the default policy' as every adult is being offered a jab by default.

1andrew1 08-04-2021 16:34

Re: Coronavirus
 
Quote:

More than 700,000 AstraZeneca vaccines sent to Australia from UK despite shortage

The shipment was allegedly kept quiet to avoid controversy as Britain faces slowdown in rollout due to supply issues

More than 700,000 doses of the AstraZeneca vaccine have been sent to Australia despite a shortage of jabs in the UK.

Australia’s vaccine rollout was boosted by a shipment from Britain that was kept quiet to avoid controversy, according to reports in the Sydney Morning Herald and The Age.

Health Secretary Matt Hancock, on Thursday morning, did not deny the 717,000 doses manufactured in the UK had been sent to Australia but said it was not the Government who made the shipment.
https://www.telegraph.co.uk/news/202...pite-shortage/
https://www.theguardian.com/society/...blocked-export

pip08456 08-04-2021 17:06

Re: Coronavirus
 
No sign of any slowdown yet Andrew. The Moderna vaccine roll out started yesteday and there's no reason to see any slowdown.

Hugh 08-04-2021 17:17

Re: Coronavirus
 
Quote:

Originally Posted by pip08456 (Post 36076517)
No sign of any slowdown yet Andrew. The Moderna vaccine roll out started yesteday and there's no reason to see any slowdown.

Unfortunately, the Government statistics show differently - hopefully, this is a blip, and it will get back to previous rates.

In the week ending 21st March an additional 3,053,371 people were reported to have received an NHS vaccination for COVID-19 in England (first dose 2,539,057)

In the week ending 28th March an additional 3,509,245 NHS vaccinations for COVID19 (both first and second doses) were administered in England (first dose 2,200,416)

In the week ending 4th April an additional 2,131,838 NHS vaccinations for COVID-19 (both first and second doses) were reported in England (first dose 670,745)

https://www.england.nhs.uk/statistic...March-2021.pdf

https://www.england.nhs.uk/statistic...April-2021.pdf

https://www.england.nhs.uk/statistic...April-2021.pdf

jfman 08-04-2021 17:39

Re: Coronavirus
 
There has always been an anticipated dip around now based on published (and then unpublished) data from Scotland in January. Scaling up from the population share of 10% the UK figures would look something like this:

W/C
22/02 1.9m
01/03 4.4m
08/03 4.3m
15/03 1.2m
22/03 4.6m
29/03 2.3m
04/04 4.1m
11/04 1.6m
18/04 3.9m
25/04 3.9m
Then 3.4m thereafter.

Hugh 08-04-2021 18:20

Re: Coronavirus
 
Probably because of the need to get the 2nd dose into people in the agreed time period.


All times are GMT +1. The time now is 08:40.

Powered by vBulletin® Version 3.8.11
Copyright ©2000 - 2025, vBulletin Solutions Inc.
All Posts and Content are © Cable Forum