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The EU approach to the vaccine issue is like the EU turning up at the AZ butcher on Christmas eve morning and ordering 90 turkeys...............
EU - "Our French supplier hasn't got any so we're short" AZ - "We'll do our best but were not geared up to give you all 90." EU - "Well you're supplying Britain?" AZ - "Yes but they ordered 5 months ago and helped build the farm. We can give you what we've got, maybe 30" EU- "But we didn't know if it worked 5 months ago" AZ - "Neither did the UK but they had faith in their science and invested money on behalf of the world" EU - "Well I'll sue you then...and tell everyone your turkeys are poisonous" Later that day... EU - "Sorry about that, your turkeys are fine but now no one wants your turkey. However even though we've got 7 spare at home, we still demand the 90 turkeys, oh and by the way this isn't our fault" |
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The EU should recognise that where a product is supplied in two parts, specially with a time constraint on it's supply, then the supplier is contractually obliged to supplied the 2nd part, once it has delivered the 1st part. Pfizer need to supply the UK with the required 2nd doses.
Perhaps the UK could reassure the EU, that any Pfizer vaccine supplied will only initially only be used for 2nd doses. |
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On Friday I booked my first Jab, which I will get Monday morning at 9:20am, best of all its a 5 minute drive away.
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How I LOLed. :rofl: |
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However some good news that should finally end the uncertainty is the outcome of the Phase 3 US clinical trials showing 79% efficacy. While not one to necessarily trust the BBC quick fire analysis the published data should let more independent sources crunch the numbers. |
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The USA says AZ is a-ok: https://www.bbc.co.uk/news/health-56479462
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The EU is threatening to hijack IP rights, but then what? They would still need to build and set up any manufacturing sites, and that takes time. Are they planning to produce AZ vaccine for a profit? |
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While there would be some scope for unscrupulous profiteering in the short term as supply ramped up to meet demand this would be limited. My only point was that limiting who can (and where) a vaccine can be manufactured creates supply side blocks. Even when the UK, EU and USA have all been vaccinated we are some considerable distance from the "entire planet" being vaccinated which was the point I was addressing about delays in the French under 55s being vaccinated. |
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The EU has set up new sites and expanded existing ones. Their problem is they left it too late and/or are for vaccines not yet approved. The world's third biggest vaccine maker, Sanofi of France, came up with duds. That will have delayed EU production massively. That was the "luck of the draw". AZ vaccine might have turned out to be a dud, as with Pfizer, Moderna, etc. |
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Clearly the manufacturers are holding exclusive rights over their own vaccines. This isn't surprising - it's industry standard. Nobody can just open a plant in India, China or elsewhere and start making the vaccines at cost without infringing on the rights of Pfizer, Astrazenica, Moderna or anyone else who has a successful vaccine candidate. |
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It takes time to expand an existing plant or open a new one. Eg Some French investment of June 2020 has yet to come online. The UK benefited from government investment in vaccine production before last year. We got ahead of the game. Link Quote:
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The word we are discussing here is Biosimilars. Which are 'generic' biological drugs. Freeing up the IP would create a big biosimilar market. A lot of countries such as India, Gulf states, Brazil, Turkey, South Africa are getting big into biosimilars.
There are some issues with skills. If you look at countries who do a lot of pharmaceutical work, you tend to find the companies are quite bunched together. Ireland is a great example with LOADS of companies based around Dublin and Cork. Ireland invested heavily some years back to grow a pharmaceutical industry through targeted education and big tax breaks. There is now a critical mass of educated people in Ireland who tend to flit from company to company and Ireland is an attractive country to set up shop now. Countries need to grow that skills base or buy it in. India is growing it, the gulf states are buying it in. One big reason why companies won't release their IP for these vaccines is that the technology can be very useful once known. Once you know how to modify and produce an adenovirus or mRNA vaccine for one disease, it takes no time to make a different vaccine. This is how the AZ and Pfizer vaccines came out so quick. Knowing how to make a vaccine quickly is great but you wouldn't want to spread that around too much. |
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It does indeed take time to expand plants and capacity. Which is why more people doing it would be beneficial. There is a block on anyone other than the candidate vaccine manufacturers (or anyone doing so under licence) from producing any of their own vaccines. As I say it’s industry standard. |
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Interesting thread (imho) on the history of this debacle
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Yay for globalisation and complex supply chains, they turned out to be such a great idea ...
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Maybe a deal to ease some forms of Indian immigration into the UK in return: Quote:
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Still a load of Nationalist tripe and politicians trying to play it for themselves. The virus and it's variants don't care about petty politics. No country is immune in the long run if the virus isn't tackled everywhere and we don't work together and share resources/vaccines.
As ever, together we win, divided we lose. Humanity will never learn, which will lead to our ultimate downfall, whether it's a virus or more likely climate change. |
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If we'd joined forces with the EU as you suggested, we'd be right up shit street nix paddle. |
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The UK is indeed one of the suppliers for the Pfizer vaccine (lipid nanoparticles) but Merck now also produces the same ingredient in the EU. https://cadmus.eui.eu//handle/1814/70363 |
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The U.K would have to respond in kind but it's probably best to be cautious before the Government starts sabre-rattling. I think the EU leadership would want nothing better than for Boris Johnson to start making counter-threats and turn this into a Britain vs EU thing for the benefit of their domestic audience.
The U.K should wait and see what they actually do. Then see if it does actually impact us. If they do a tokenistic block of some vaccines from some factories then we should roll our eyes and take the moral high ground leaving the EU looking petulant and ineffective. If they do start making a notable impact on our vaccine supply and schedules then we have to respond by blocking the export of the ingredients needed. We should also make overtures to European-based pharmaceutical companies to move more production to the U.K on the promise we won't block them from honoring their contracts. |
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In general for a limited production product, it is first ordered, first supplied. The UK has ordered 100m doses of the AZ vaccine. The language used at the time of the pre-order strongly implied that the UK was at the head of the queue for being supplied. That was 3 months before any EU-related deal. |
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https://www.nih.gov/news-events/news...zeneca-vaccine
Americans kicking up a fuss (again) about Astrazenica paperwork from the clinical trial, potentially using outdated data that could skew efficacy and urging them to "ensure the most accurate, up-to-date efficacy data be made public as quickly as possible". Be interesting to see if this holds up FDA approval. |
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Nobody would gain from arbitrarily export controlling raw materials |
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I'd like to put something forward that touches both Covid and Brexit.
1/ Covid doesn't care about the EU or the UK. But Covid has laid low both the EU and UK. 2/ Accordingly, Single Market, Free Movement, Customs Union - they have little relevance to the UK in the Covid context (not speaking for other EU countries). 3/ Covid is something where the population are important stakeholders. The EU, as we know, is not a nation state. To act on behalf of all EU nations where there is no particular competence (as with Covid), the agreement of all 27 members is required such that specific powers are conferred on the EC. 4/ What would have been the case if the UK had been an EU member? Is there a clue when, in the transition year, the UK was invited to join the EU vaccine procurement collective? Presuming that the Oxford Vaccine (and AZ) were all lined up from earlier in the year, I don't think the UK government would have wished to support the EU proposition. 5/ But then if May had remained PM, she would almost certainly have locked on to the EU proposition. 6/ Because the need to survive (a pandemic) trumps everything except public order, the UK people expect the government to pay close attention to its own. The EU is proving itself to be an enemy - a real enemy. I think that Boris' current approach, in so far as we can glean, is the right one. Not to threaten, maintain reticence, hold the line and let the EU keep on being the bad boys. 7/ How right we were to leave the EU. Our lives matter more than the Single Market. |
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1. Funding vaccine research well before covid became a problem in the UK 2. Insisting that the eventual product must be manufactured in the UK so that supply to the UK could be assured 3. Ensuring terms relating to priority of supply were written in from the outset, and 4. Ensuring those terms were rolled on to AsraZeneca when it received the contract to manufacture. UK priority does not arise from a later, but better, agreement than the one the EU signed. It arises from funding, negotiations and a priority of supply agreement between the UK and Oxford, and latterly AZ, that was all in place much, much earlier. In this context the UK’s later conclusion of purchase terms is irrelevant - all the important supply terms were already in place. |
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It might also make Governments rethink incentives to push people to get vaccinated if the herd immunity threshold is only going to be achieved with near 100% uptake. |
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Do get out old chap, its a lovely day, spring flowers, birds singing etc. ;)
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As things stand, the EU is so large and behind in vaccinating people, that whatever is done it will be a long time before it would be safe for people from the EU to come here. If pretty much the whole of the UK has been vaccinated, then there would be a lot less risk in allowing people to come here, and for people from the UK to go elsewhere(eg Spain). If X% of the UK were not yet vaccinated, that X% would be at risk from EU visitors, or to the EU if they went there. One EU leader gets it. Quote:
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If they go so far as to ban vaccine exports, then the UK is in a life threatening position. All trust and conciliation would be lost and we might as well abandon the treaty because of the EU’s act of aggression. We can build trade elsewhere. The EC is a nasty, vindictive executive and if the 27 nations back what the EC proposes then there is little point in pretending that they are worthwhile partners. |
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I pay my taxes for the UK government to protect me, not France, etc. I expect the government to act accordingly including red-listing EU countries immediately. |
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May I butt in with a couple of questions?
Has it yet been proven that the vaccine prevents you from catching Covid-19? If it doesn't, can you catch it and spread it to others? If you've had the first and second jab, then go out and mingle with people who have tested positive, would you still be 'told' by track & trace to isolate for a week? It seems (to a fikko like me) that there are more grey areas than a library (remember those? ) full of pensioners :D |
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For him. Few days leave from this topic granted. [Amended to at least 2 days] Cable Forum Topic holidays. ATOL Protected. |
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I am not taking part in any silences or clapping. I'm not patting this government on it's back particularly for the shabby way they are treating the nurses when if they had locked down at least a month earlier more lives might have been saved. Closing the borders was the FIRST thing they should have done.The only thing they got right was supporting finding a vaccine which was the very least thing they have done. The ONLY people who deserve any accolades are the key workers which is better dealt with by paying them a decent wage and hopefully a bonus.
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The US has been doing this since day one of course with a ban on vaccine exports. |
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Here's a really good article on this here - https://www.nature.com/articles/d41586-021-00450-z The best way to answer your questions is to do a challenge test where some hardy souls/heroes/people desperate for cash/complete mugs get deliberately infected with SARS-COV2. A trial is about to be started here in the UK - https://www.gov.uk/government/news/w...oval-in-the-uk |
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With ITV missing out on Love Island this year due to the pandemic, this would seem like an ideal prime time schedule-filler for them. :D |
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Celebrity Covid, finally we get a reality TV program worth watching :tu:
Heck, I may even be inclined to join the public telephone vote as to which one gets the placebo :D |
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Vaccines vary a lot in how much they stimulate the immune system. It does depend on how 'foreign' the disease is. A 'good' disease is one that can escape the immune system by either disguising the parts which the immune system recognises - see HIV or changing rapidly - see influenza. You can help a bit by adding other agents which also stimulate the immune system. These are called adjuvants. When you hear about aluminium in vaccines, that is aluminium hydroxide powder which makes your immune system go crazy. It can also help by administering the vaccine through the same route as the disease (see Flumist flu vaccine and Polio vaccines) but that is really hard to do so they mostly get injected. |
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https://www.washingtonpost.com/world...9ac_story.html
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Had the EU come to the UK and quietly asked if we could help them out, then I would have expected a an accommodation with 'our European friends". However, Macron and Merkel publicly trashed AZ vaccine to the extent that there is major public resistance to that vaccine. The above said, I'm sure that the UK government will offer something to the EU, which they don't deserve. |
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I've got a snooker cue, some golf clubs, and an unused season ticket they can have, no use to me :(
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https://www.aol.co.uk/news/stanley-j...UWUTQSLSisQpL5
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S.J., Winsford, Somerset ;) |
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If that was the scientific advice, then you cannot correctly blame the government for getting it wrong. Whitty said: "...if we go too early, people will understandably get fatigued and it will be difficult to sustain this over time". Wasn't it the World Health Organisation that was advising against closing the borders because "evidence shows that restricting the movement of people and goods during public health emergencies is ineffective in most situations and may divert resources from other interventions"? The government had a lot to weigh up in those early days and was receiving conflicting advice due to the many unknowns, not to mention fears for the economy. Blaming the government for anything that went wrong is a cheap shot. |
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What Whitty’s public statements on early/later lockdown were made are irrelevant. He’s not going to go out and publicly say something against Government policy. By that point the decisions have been made and lines agreed, unless he fancies resigning. Pointing to discredited WHO advice is a red herring and by mid-March many other countries were going against it. |
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1. We have enough AZ vaccine to meet our 2nd dose needs; 2. We are vulnerable to EU action on 2nd dose Pfizer needs; 3. The UK should bail the EU out as there will be returns for us. Quote:
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Millions of elderly? Even Professor Pantsdown wasn’t that much of a doom-monger.
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If you think about how you get infected with SARS-COV2, you need to get close enough to someone who is shedding virus and breathe in virus particles in a high enough dose. Symptomatic people are a huge issue and they will coughing away and shedding a lot more virus in to the air so not only is virus coming out, it's getting forced out at speed (evolution is great!) BUT, at this stage, if you are symptomatic, in all likelihood you are going to think 'Uh oh, COVID' and isolate and get tested. Also, masks will help catch the droplets being sprayed out by a symptomatic person. Logically, an asymptomatic person will be less infectious as they aren't coughing but the evidence is weak right now on how much less infectious they are. Kids are more likely to be asymptomatic, hence the in school testing going on right now (I have a big stack of test kit boxes on my dining room table right now for home testing of the kids) Te downside of asymptomatic people is that they are not isolating - they are merrily going about their way shedding virus. What we need to know is what the 'R' value is for an asymptomatic person and that isn't clear right now. So, vaccines seem to reduce the numbers of people actively spreading SARS-COV2 by coughing and the numbers of people unwittingly spreading infection and the infective period seems less so, in all likelihood, vaccines will reduce transmission as there are less people spreading the virus. What is less clear is how infectious you are if you are vaccinated but infected. This is one of the reasons why the Government is asking vaccinated people to not go crazy (there are other behavioural reasons too of course) |
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I had my Oxford AstraZenecia jab on Monday morning.
I woke up on Tuesday feeling like I had a cold, and just rundown, my Brother in-law had his just before me, but he felt like crap. This morning we are both getting back to normal, and one step closer to family hugs. |
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At last I can add the 2nd jab to my Covid Symptons Study app. Worth having a look at the results of the study if you haven't come across it before. https://covid.joinzoe.com/ |
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EU is getting a bit paranoid.
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It is a fact that Whitty said that, and if you remember, the government has always said that they were following scientific advice. The WHO advice may have been discredited subsequently (if you say so) but the fact is, that’s the medical advice that was there. Government decisions? Yes. Medical advice at the time? Yes. What other countries were doing, frankly, is irrelevant. |
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You’re quoting one man on Government payroll and giving that greater weight than the scientific advisory groups the Government appointed to give advice. Ministers make decisions based on (or against) that advice at their own discretion. |
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Wing Commander: I want you to lay down your life, Papa. We need a futile gesture at this stage. It will raise the whole tone of the war. Get up in a crate, Papa, pop over to Bremen, take a shufti, don't come back. Goodbye Papa. God, I wish I was going too.
Papa: Goodbye sir - or is it “au revoir"? Wing Commander: No, Papa... (thank you, Peter Cook) |
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This looks like a thoroughly meaningless statement.
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It didn't take our "EU friends" long to revert back to being the old enemy :(
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SAGE may have thought differently at another point in time, but there were many other factors that had to be taken into account, and not all of them were medical issues. You are over-simplifying this to an extraordinary level to try and win your unfounded argument. But to try to paint a picture that the government was not listening to medical and other professional advice is just fanciful. |
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What is fanciful is the idea that the Chief Medical Officer, or Chief Scientific Adviser, could or would go public and make statements that actively contradict Government policy as agreed by Ministers. You are greatly over-complicating the situation to allow yourself to claim that the Government have been blameless at all times. Over lockdowns, PPE, billions for Dido Harding’s non-functioning contract tracing... always someone else to blame. |
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Badly handled
I think Boris's performance is improving whilst some other leaders are worsening, eg Angela Merkel and her last-minute Easter extension which the country revolted against. |
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This was a unique situation and we were dealing with the unknown. It’s all very well slagging off the government no matter what it does from the comfort of your own armchair, but I shudder to think about what a pig’s ear the other lot would have made of it. Captain Hindsight would have been facing the wrong direction throughout. Corbyn would have consulted Hamas. At least this government has been decisive, and they have certainly come up trumps with vaccine procurement and the subsequent action to ensure prompt vaccination of the population. Meanwhile, EU deaths are set to escalate with the start of a new wave that their population is fully exposed to. |
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I think the government has been careful in its decision making this year.
A year ago, they screwed up royally in not managing the care home situation. As to the science officers, Boris knows that Witty is trusted by the people and this is what has made Boris become more circumspect. |
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Surely the EU can just "shield the vulnerable"? :dunce: I see you've at least dropped that ludicrous tagline from beneath your user name. The fact other governments could have made better decisions is neither here nor there to your original claim that I debunked - as I say it's a matter of public record - that they ignored SAGE advice on both lockdowns and this had a catastrophic impact modelled as tens of thousands of deaths. |
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London along with the rest of the country. Quote:
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The Government have to take in advice from many areas, attempt to weigh the pro's and con's and proceed accordingly. Don't forget the SAGE advice was based on modelling since shown inept at best. The current models for unlocking are not based on seasonal changes or actual vaccine take up so how can they be trusted? Cases reducing, hospitalisation reducing, deaths reducing P-leasssse. It has still yet to be proven that lockdowns actually work, they may in the short term to reduce pressure on hospitals but do they work overall? Many people look to the far east to prove the effectivence of lockdowns/mask wearing without factoring in societal differences. New Zealand is often brought up as an example but far easier to control the spread than any other 1st world country. As Society is responsible for everything it does for and on behalf of itself why should any Government need to legislate what that society does? |
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Lockdowns work overall - of course they do. It just depends what your “overall” is. The overall aim of a lockdown is to get transmission low enough for hospitals and the economy to function. The overall aim is not to eliminate covid from the population, regardless of what anyone says (Nicola Sturgeon liked to suggest she had a zero covid strategy in the early days ... she has quietly dropped that now). For quite some time now it has been acknowledged that a vaccine is the only actual exit route from the disruption to our lives.
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Helps SAGE with their scaremongering. ---------- Post added at 23:02 ---------- Previous post was at 23:00 ---------- Quote:
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As I said, there were other aspects over and above the Sage advice that needed to be taken account of. The government listened to ALL the arguments. Taking a different decision does not necessarily mean you ignored the advice. It was not taken for the reasons we will hear about when the review is forthcoming. |
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To those of you wondering about the Zoe app Maggy posted earlier (perhaps not this tread) here's more info.
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As for your final point why have a speed limit? Require seatbelts? There’s a whole swathe of activity Governments don’t trust individuals with. ---------- Post added at 06:47 ---------- Previous post was at 06:44 ---------- Quote:
I eagerly await the review. The trailers for the bold Dom’s evidence have been good so far. |
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It was joglynne (I’ve been taking part too, along with 4.6 million others)
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On your second comment, it falls down when public health is involved unless society provides its' own healthcare service. It's governments role to keep us safe. It's why we have the police, army, etc. If suggesting and asking nicely to act safely doesn't work, then governments legislate. It's why we have speed limits. As I have said before, we in the UK are 'soft' when it comes to healthcare as we know that the NHS will always be there if we mess up. If that safety net weren't present, people would be a lot more careful! Libertariansim like communism is a nice idea on paper but doesn't work in the real world. |
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Sorry Maggy. |
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