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I wish I could get the vaccine. I am not that worried about catching COVID in terms of my health and don't take any precautions other than vaccinations but I had it in early August and it was just annoying.
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So the idea of the bivalent vaccine is that you're injected with the original spike and also the spike of the (original, as it's all they had) omicron. Mutations in the more recent omicrons such as BA.5 are less drastic when compared to this than the previous spike protein is, so the immune system recognises it better. This will mean that the response the immune system can give to the vaccine is much better (in principle, I doubt there's a great deal of real world data outside clinical trials yet) which usually means it can respond with meaningful antibodies and t-cells quicker. Despite that it's probably not going to be perfect and some people will probably still get covid when they have had it and may be able to transmit it without getting ill but better levels of prevention are clearly more helpful in general. As for workplaces you're around people all day and if someone's sat at their desk coughing all day because they have covid then if the rest of them aren't vaccinated then they'll probably all get it. If say the original vaccines offer like 20% (hypothetical figure) protection against getting ill from covid then if there's 10 people sat near them all day then 8 of them will get it. If that figure is reduced by bivalent vaccines to 80% then only 2 will get it (again that is just illustrative before you nit pick it). And if only 2 people out of a usual team of 10 were well enough to work then whatever they're doing will be severely impacted for a few days at least whilst they get over covid. |
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No need for me to nit pick, you've acknowledged yourself it's hypothetical. And the theory is sound, now if someone could develop a vaccine that had efficacy against infection, that'd be nice and I'd be in the queue.
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None of them actually prevent anything, they just reduce the risk of getting it. That's the case for any covid vaccine and indeed the ones against other illnesses. We're just noticing it more with covid as the virus has changed and the number of infections is high enough for even a 99% successful vaccine to still allow 1 in every 100 infections to break through protection. If 100k people are getting covid a day as was happening last winter then 1. the vaccine is going to prevent a lot of these no matter how effective it is 2. the majority of these are going to be prevented from serious illness by having a better immune response If you think of other illnesses there isn't a vaccine against norovirus because the virus mutates often enough so it can't really work and also there isn't really much benefit from vaccinating against something which just gives you a bad stomach for a couple of days then stops in most people, flu vaccines are different as they are targeting a predicted strain which they think might go round and if this is wrong a lot will still get it and even some vaccinated people will still get flu. Think of immune response to a vaccine as meeting someone for the first time. You have a photo of them which was taken last month and have to pick them out from a crowd and take them somewhere. Now if you have a recent photo this won't take long and will be quite easy. Now imagine the photo is 5 years old. It's still that person but they might be a bit fatter, hair might have gone a bit grey, they might need to wear glasses now, this takes longer. Now imagine the building's on fire and you need to recognise them and get them out before too much burns... Or they need to be somewhere quickly to stop the fire. The more recent photo is likely to mean the fire causes less damage. This is why the older vaccines are less useful now. Quite frankly I don't see the point in offering anyone the vaccines which aren't bivalent now, unless there's a clinical reason why you can't. They need to join masks and lockdowns in the "things which don't work now" pile. |
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There’s no real world evidence to demonstrate efficacy against infection of the current vaccines against current variants at all. In six months when we are two more waves and variants on, the gap will be even wider. Hybrid immunity is clearly not up to much either, despite it’s many proponents. This is my last input on the subject for now the thread was dead and buried and I’ve no real interest in resuscitating to debate the palpably obvious. |
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How does the immune system ward off attacks by viruses and bacteria that are not yet inside the body?
Many types live on our skin and are ignored. But once they get inside (infect), the war begins, helped by vaccines that have taught the immune system what they look like, act like and what toxins they produce. |
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I got my 4th shot and flu jab last Wednesday, no ill effects at all.
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On Friday I was extremely tired, so much so that I basically slept from Thursday night until this morning. I suppose this will have been the vaccine working it's way into my system. |
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The CDC followed about 10 million jabbed people and their data (released after a year of foi requests and two court orders) shows that 7.8% of people who got the jab needed medical treatment afterwards and 25% couldn't go to work or school for a period of time after the injection. ---------- Post added at 20:03 ---------- Previous post was at 20:01 ---------- Quote:
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Just so you know, I have had multiple flu jabs, and multiple covid jabs, and not a single side effect from any of them. Of course, you could equally say that 92.2% of people who got the jab (which jab ?) needed no medical treatment afterwards, and that 75% could go straight back to school or work again. :) As Ive posted in the past, all vaccines do is prepare your body to deal with a virus, they do not prevent, or cure. However, if they do the job well, your body kills off the invading virus before you notice, so it appears they prevent infection. By the same token, if the virus in you gets killed off quickly, there is little chance of you passing it on, so it appears to prevent transmission. |
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Thank heavens for some sensible people on this site.Paul,Hugh and Chris.:clap:
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https://www.bhf.org.uk/informationsu...20even%20lower. Quote:
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edit: Anyway, I'm not saying anymore on this subject. :) |
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Research online. The info isn't all that hard to find :)
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Anyone with a smartphone and 10 minutes on the bog can do it ;)
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If,you really want to know, the Medicines and Healthcare products Regulatory Agency report side effects reported to them on a monthly basis through the Yellow Card scheme. Here is their current report - https://www.gov.uk/government/public...card-reporting
This is the raw data so there might or might not be a real link between the reported issue and the vaccine and the reports are very clear on this. Anyone can report side effects here - https://coronavirus-yellowcard.mhra.gov.uk/ |
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Sorry but I have zero tolerance for conspiracy nuts and their websites. Any fool can “do their research”. The problem is, fools lack the analytical skills to evaluate raw data and reach balanced conclusions. Covid vax conspiracies are the domain of fools. And that’s really all there is to it. |
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It's the same for VAERS in the USA. ---------- Post added at 18:00 ---------- Previous post was at 17:59 ---------- Quote:
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You can only work with the data you have of course. The Yellow Card scheme is not a clinical trial level of data collection as it relies on active reporting. However, it does give a guide to what is happening in the field. I did watch the clip. She is claiming that the vaccine caused her issues. That may or may not have been the case. If it was, that is a terrible thing for her but all the evidence points to this type of side effect being very rare. No drug is without risk but that risk needs to be balanced against the clinical need. No one is hiding the potential side effects of these vaccines, a leaflet was handed out at the time of administration. The Yellow Card scheme is useful to highlight rare but serious side effects that only are seen when the pool of people having the vaccine gets much larger. |
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Even if you did believe the yellow scheme is underreported to the tune of 99% or whatever then you also need to assume that every other regulatory body across Europe and the Western world, i.e ones we trust, are wrong too. America, Germany, France, Japan, Canada, Australia.....
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edit: and the underreporting isn't what I believe. I was taught it 30+ years ago and current literature states the same. |
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https://www.theguardian.com/media/20...ark-steyn-show But the key thing is surely the statitical significance - two people out of a UK population of 65m is a low number. |
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Lmfao. I trust GB News a lot more than that hard lefty rag, I wouldn’t mop up cat piss with. |
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I think it's up to the individual to consume information from all corners and decide for themselves.
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It's common knowledge in the medical professions. |
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Under reporting is an issue but once you have a handle of when and why potential adverse reactions are not reported, you can at least correct for it to some extent. It’s not ideal but the self reporting system most regulatory bodies including the MHRA use is the ‘least worst’ option for post-market surveillance |
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You read find the Ofcom story on other sources than The Guardian if you like eg https://pressgazette.co.uk/ofcom-gb-news/ https://www.ofcom.org.uk/news-centre...ews-mark-steyn |
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It was published a year and a half ago so I thought I'd do a search on https://pubmed.ncbi.nlm.nih.gov/ to see what the MHRA had found and published. I couldn't find anything on this subject using the search terms "MHRA" & "COVID-19 vaccine safety", "Commission on Human Medicines" & "Expert Working Group" & "COVID-19 vaccine safety" That page states that there will be "Four main strands of our proactive vigilance": The first is that they will keep an eye on the yellow card reports....great, those are rubbish to begin with. The second is a form of active surveillance known as ‘Rapid Cycle Analysis’. This method involves proactive, weekly analysis of a range of pre-defined events (theoretical side effects) to quickly identify safety signals. The trouble is that Pfizer and our Govt deny that there are any side effects/they can choose to only look for side effects that they know will be very rare (not the first time that kind of thing has been done) The third is targeted active monitoring of certain groups of vaccinees. This might bear fruit. However, the CDC did a similar type of thing and it took a FOI and two court orders to get the data out of them. Their data showed 7.8% needing medical treatment for side effects and 25% not being able to work or go to school for some time after the jab. It remains to be seen whether the MHRA will find similar results. But as I said above, I've not seen anything published by them either way. There is also plenty of room to monkey about with the data as it seems to be a case control type study. The fourth are formal epidemiological studies. Just glancing at the overview of the HPV study that is linked to I see a few problematic issues: It relied on the yellow card system It used estimates of vaccination coverage That's without doing a deep dive into the full paper..... That page finishes off with "The MHRA will operate a transparent process. On a regular basis, the MHRA will produce an up to date summary of the safety experience, including aggregate Yellow Card reports, on our website." I clicked the link and found that they have published all the vaccine manufacturers data from the yellow card scheme: Non lethal adverse events: 156996 Deaths:103 Remember, yellow card data is a fraction of what is actually happening. iirc, the swine flu vaccine was pulled after something like 25 deaths. |
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We now have probably the biggest cohort for any post marketing surveillance in history. We are also developing better and better tools to analyse the data gathered, cross linking vaccination records with other medical records. If the post market surveillance for the COVID vaccine scheme is not sufficient to give confidence in the products, then I would be very wary of almost any other drug on the market as in almost all cases, the monitored population will be less than seen here |
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Jab 4 now installed :D
[ Pfizer again .... ] |
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Jab #4 booked for the 11th of November.
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On top of that, the Rapid Cycle Analysis discussed in that previous link actively data mines 13 million patient records in the UK. There are of course rare incidences of serious side effects but there will always be a risk/benefit calculation performed ================================= Edit - Found the global database of adverse drug reactions. Vigibase run from Uppsala in Sweden is the WHO run database |
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I think there are other benefits to the vaccination programme that are harder to measure. For example if those vaccinated are not going to A&E for "covid symptoms" that they don't need to turn up for because they are vaccinated and believe the vaccine will "protect them" then you reduce demand/load on A&E. (Conversely some won't turn up when they should for the same reasoning.)
Some people will feel better because they are vaccinated because they believe they will not get as sick. Mental attitude can affect physical health. I'm sure there are other factors too. |
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An interesting paper:https://insulinresistance.org/index....le/view/71/224
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Would you rather not know?! |
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Which has killed more, the virus, or the vaccine ?
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The death rate is rising, though case numbers are still low (probably because testing is very low these days).
Reporting is still every 7 days. This graph is for the period from 1st January this year to today. |
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Going to have another jab tomorrow.
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Got my Jab booked for 11th Nov, it was annoying as I got the NHS letter weeks ago saying I was now able to book it but when trying to it said I wasn't yet eligible, it's only now the site lets me and I didn't have to answer any stupid questions like.... Am I pregnant? I'm male for god's sake!!! I gave my NHS number so they should know this!
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That's all 4 of us jabbed. In-and-out in 6 minutes. Comirnaty bivalent for me.
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Comirnaty Bivalent indicates that it’s the new vaccine with protection against original covid and Omicron. |
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Moderna vaccine (Spikevax bivalent) triggers a strong immune response against both Omicron (BA.1) and the original 2020 strain. In an exploratory analysis the bivalent vaccine was also found to generate a good immune response against the Omicron sub-variants BA.4 and BA.5. My undemanding is that Comirnaty is currently being tested for its effect on Omicron sub-variants BA.4 and BA.5. |
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If you don't want to be vaccinated that's up to you but I think it's wrong to push you're agenda on other people. I do however feel people who make the choice not to be vaccinated for no reason other than they don't want to should expect to pay the cost of their care (or a good chunk of it) if they subsequently end up in hospital. |
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Regarding the unvaxxed paying for their own care, fine, just give me back my tax and NI that I've payed towards the nhs. |
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I had Covid at the beginning of July and gave it to my dad.
That probably saved his life, as a week later he had a perforated ulcer of the bowel and the limited amount of food in his system meant the infection he had could have been a lot worse, but 3 times I slept on my sister's sofa waiting for the call to come and say goodbye, but he's pulled though and should be home soon. |
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https://www.medrxiv.org/content/10.1...2280963v1.full ---------- Post added at 14:07 ---------- Previous post was at 14:06 ---------- Quote:
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---------- Post added at 16:02 ---------- Previous post was at 16:00 ---------- PEER-REVIEWED CASE REPORTS SHOWING CAUSALITY OR STRONG ASSOCIATION BETWEEN COVID-19 VACCINES AND INJURY OR DEATH |
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---------- Post added at 18:07 ---------- Previous post was at 18:06 ---------- Quote:
edit: Did either of you actually click the links to get through to the peer reviewed, medical research papers?....and read them? |
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Studies which are actually reviews of other studies rather than newly designed and conducted research have serious limitations, amongst them the risks of selectivity and confirmation bias. Sure, you have a veritable rogue’s gallery of all the very worst things that could happen as a result of having a covid vaccination, but you don’t need to trawl the internet for that sort of stuff. Every packet of paracetamol has a leaflet in it with a list of horrible things that can occur if you take it. A list of things that could happen when you take medication does more harm than good when it is divorced from its context, which is what you very effectively did here. |
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Here are links to the wikepedia/linkedin pages of the authors (that you called quacks) so you can look at their credentials(look at their education): https://en.wikipedia.org/wiki/Peter_A._McCullough https://en.wikipedia.org/wiki/Stephanie_Seneff https://www.linkedin.com/in/anthony-...alSubdomain=gr ---------- Post added at 22:20 ---------- Previous post was at 22:16 ---------- Quote:
Really?....I simply couldn't be bothered to change it to lower case. Click the link. :dozey: ---------- Post added at 22:30 ---------- Previous post was at 22:20 ---------- Quote:
btw...The total side effects for the cov vax's (in the last 2.5 years) are more than all side effects for all vaccines in the last 40 years. Latest one, iirc, was tested on 6 mice! ---------- Post added at 22:34 ---------- Previous post was at 22:30 ---------- I have no words. I'm posting up to date medical research and you are judging my posts because they have bullet points that you find upsetting and the url link is in capitals? Realy? That's your argument? |
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edit: What accusations am I making that you are upset about? btw.....Chris called me a quack....that's an insult. I'm insulted now. Care to comment? |
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I have less issue with the limitations of a ‘survey of surveys’, which is what this study is, than I do with the headline you chose to put on it. You’re obviously pursuing an agenda. I don’t need to read the entire research paper to know that. And yes, I could if I was so motivated. While neither of my degrees are in the sciences, I believe I’m competent to read and evaluate the material adequately well. |
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1. I said people, not me, but you knew that already. You are perfectly well aware what you said, and to who, since you went back and edited it again after I removed it (we store all edits). 2. Are you blind, or just playing dumb. I quoted it. 3. No, he didnt, I suggest you go back and read it again. TBH, I think you are just playing the troll now. I advise you to move on and not to continue picking this fight. |
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2) You do need to read the entire research paper, and you should know that. |
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From the first of RamRod's Wikipedia links:
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I think that link tells us all we need to know about the report's credibility! And ironically, it was provided by RamRod himself in an attempt to support his case! |
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As I said, just playing the troll now, I have no interest in your games, have a break from this topic.
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On peer review, and by extension randomised controlled trials, and as is Friday night and I’ll declare myself as being five bottles of beer in I present the PARACHUTE study. Proving that jumping out a plane your survival chances, or chances of injury, are unchanged based upon parachute use.
https://www.bmj.com/content/363/bmj.k5094 |
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https://en.wikipedia.org/wiki/Food_a...cal_Toxicology See section controversies "In 2022, after a call from the editor for articles on alleged adverse effects of the Covid-19 vaccine,[7] Seneff et al. published a paper alleging various mechanisms for various diseases that the authors intend to link to Covid-19 vaccination.[8] Several scientists have warned of the biases and shortcomings that this article contains.[9][10][11][12]" Let's wait and see whether the paper you mention will be retracted as the other one. Seneff is well known, she is an expert on many things including weedkillers. See her wiki page, it is full of controversies. She publishes in MDPI journals that are not really reputable. |
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