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-   -   Coronavirus (OLD) (https://www.cableforum.uk/board/showthread.php?t=33708712)

jfman 15-04-2020 11:10
Re: Coronavirus
 
Quote:
Originally Posted by tweetiepooh (Post 36031709)
And what happens if we get COVID-20/21/22/23/30? Are they going to be like the cold so keep returning and reinfecting?
It's highly unlikely, however we should be prepared. Have PPE available and a mechanism to quickly scale up testing. Intervene early, screen people at airports and isolate them as appropriate and contact trace. It's not rocket science and while moderately expensive by 2019 terms it's a relative bargain compared to a 35% drop in forecast GDP.

tweetiepooh 15-04-2020 11:19
Re: Coronavirus
 
Quote:
Originally Posted by jfman (Post 36031716)
It's highly unlikely, however we should be prepared. Have PPE available and a mechanism to quickly scale up testing. Intervene early, screen people at airports and isolate them as appropriate and contact trace. It's not rocket science and while moderately expensive by 2019 terms it's a relative bargain compared to a 35% drop in forecast GDP.
That is all true, herd immunity to a changing target is not likely. I think we also need to work globally and share more both is resource and information. If we can shut down infection closer to source before it spreads that becomes much easier to manage and is likely to be cheaper in the long run. That would mean maybe producing equipment that is portable so if infection starts in 3rd world it can be used there.

denphone 15-04-2020 11:25
Re: Coronavirus
 
Hopefully consumers should find it a little bit easier to get hold of paracetemol after this deal.

https://www.gov.uk/government/news/u...of-paracetamol

Hom3r 15-04-2020 12:54
Re: Coronavirus
 
On a very positive side


A 99 year old Captain Tom Moore wanted to raise £1,000 for the NHS buy walkiing 100 lengths of his garden.

Well as of 12:58pm on the 15th of April.

It's at £6,305,649.00.

The Just Giving site is struggling to refresh, at one poit 90,000 people were donating at the same time.

https://www.justgiving.com/fundraisi...swalkforthenhs


A Pride of Britain award bekons

Maggy 15-04-2020 12:56
Re: Coronavirus
 
What we need is rain and lots of it..That would keep more people indoors.

Sephiroth 15-04-2020 13:53
Re: Coronavirus
 
Quote:
Originally Posted by mrmistoffelees (Post 36031707)
The herd immunity that we don’t know will work ?
<SNIP>
You are right, of course - but then the vaccine when it comes may also not work for the same reason unless they've found a clever killer add-in.

---------- Post added at 13:53 ---------- Previous post was at 13:51 ----------

Quote:
Originally Posted by Hom3r (Post 36031721)
On a very positive side


A 99 year old Captain Tom Moore wanted to raise £1,000 for the NHS buy walkiing 100 lengths of his garden.

Well as of 12:58pm on the 15th of April.

It's at £6,305,649.00.

The Just Giving site is struggling to refresh, at one poit 90,000 people were donating at the same time.

https://www.justgiving.com/fundraisi...swalkforthenhs


A Pride of Britain award bekons
... in addition to the Queen's telegram. Another medal to add to his row.

Paul 15-04-2020 14:27
Re: Coronavirus
 
Quote:
Originally Posted by Maggy (Post 36031722)
What we need is rain and lots of it..That would keep more people indoors.
Not much fun queueing at the shops / supermarket / pharmacy though :(

ianch99 15-04-2020 16:04
Re: Coronavirus
 
Quote:
Originally Posted by pip08456 (Post 36031686)
I think all of us echo what Chris has said.
Hear hear ..

---------- Post added at 16:04 ---------- Previous post was at 15:53 ----------

Quote:
Originally Posted by jonbxx (Post 36031698)
It looks like the big boys, namely Glaxo Smithkline and Sanofi Pasteur are getting together to work on a vaccine - https://www.sanofi.com/en/media-room...04-14-13-00-00

These guys know their stuff and critically have the manufacturing scale at their plants in Belgium and France to get things done
If the vaccine is being manufactured in the EU, does that fact that we have left the EMA affect timely access to the vaccine?

pip08456 15-04-2020 16:22
Re: Coronavirus
 
Quote:
Originally Posted by ianch99 (Post 36031736)
Hear hear ..

---------- Post added at 16:04 ---------- Previous post was at 15:53 ----------



If the vaccine is being manufactured in the EU, does that fact that we have left the EMA affect timely access to the vaccine?
As we are still in the transition we are still in the EMA.

heero_yuy 15-04-2020 16:58
Re: Coronavirus
 
GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source

jonbxx 15-04-2020 17:13
Re: Coronavirus
 
Quote:
Originally Posted by heero_yuy (Post 36031740)
GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source
GSK doesn't really have vaccine manufacturing in the UK. The bulk of the local vaccine manufacturing is in Rixensart in Belgium. Blimmin huge site that too. However, it's not clear if the vaccine final formulation will be Sanofi, GSK or both.

(super geeky background, GSK is very good at whole viral vaccines, especially egg based products. Sanofi good at viral component vaccines)

On the regulation, the UK regulator (MHRA) is being super flexible on regulations so we would very likely take EMA approval directly even if approved after the end of the transition period. Where there's a will, there's a way...

mrmistoffelees 15-04-2020 19:12
Re: Coronavirus
 
Quote:
Originally Posted by Sephiroth (Post 36031726)
You are right, of course - but then the vaccine when it comes may also not work for the same reason unless they've found a clever killer add-in.

---------- Post added at 13:53 ---------- Previous post was at 13:51 ----------


... in addition to the Queen's telegram. Another medal to add to his row.
Hence clinical trials

Pierre 15-04-2020 21:40
Re: Coronavirus
 
Quote:
Originally Posted by jfman (Post 36031716)
It's highly unlikely,
Even though you are CableForums most eminent chief virologist, the correct answer I think would be, we don’t know.

Unless you’ve done the research, of course.

Quote:
Have PPE available
Absolutely, I think a national store of PPE is required, depends on the shelf life as to how much we can stockpile.

Quote:
a mechanism to quickly scale up testing
Yes a “mechanism” - don’t know what it is, but we should have it.


Quote:
Intervene early, screen people at airports
Proven not to be effective during this pandemic.

https://www.eurosurveillance.org/con...0.25.5.2000080

Quote:
Due to the duration of the incubation period of 2019-nCoV infection, we find that exit or entry screening at airports for initial symptoms, via thermal scanners or similar, is unlikely to prevent passage of infected travellers into new countries or regions where they may seed local transmission.
I’m going to downgrade you to “junior virologist” for this error.


Quote:
isolate them as appropriate and contact trace.
isolate them based on airport screening that is too inaccurate?

Quote:
It's not rocket science
it certainly isn’t, it’s infectious disease management, when you don’t know the disease and you don’t know how infectious it is, you don’t know the mortality rate, you don’t know how if affects each individual............in short you know sweet FA about anything and you have to make decisions everyday based on the data of the previous day.

---------- Post added at 21:40 ---------- Previous post was at 21:35 ----------

Quote:
Originally Posted by Paul (Post 36031731)
Not much fun queueing at the shops / supermarket / pharmacy though :(
I find the whole thing very civilised. I appreciate it may vary depending where you are and whilst the weather is good.

But I happily queue for about 5-10mins to get into my local Tesco or CoOp and it’s all very chilled and relaxed.

Damien 15-04-2020 21:59
Re: Coronavirus
 
Quote:
Originally Posted by heero_yuy (Post 36031740)
GSK in the UK is working with its French rival on the vaccine so it's likely that it'll be manufactured in the UK as well so no need for the EU involvement.

Source
Quote:
Originally Posted by jonbxx (Post 36031741)
GSK doesn't really have vaccine manufacturing in the UK. The bulk of the local vaccine manufacturing is in Rixensart in Belgium. Blimmin huge site that too. However, it's not clear if the vaccine final formulation will be Sanofi, GSK or both.

(super geeky background, GSK is very good at whole viral vaccines, especially egg based products. Sanofi good at viral component vaccines)

On the regulation, the UK regulator (MHRA) is being super flexible on regulations so we would very likely take EMA approval directly even if approved after the end of the transition period. Where there's a will, there's a way...
Also the EU thing really won't matter here. There is a lot of money being thrown at this and as soon as a viable vaccine is found it'll be produced on a scale never seen before.

Paul 15-04-2020 23:44
Re: Coronavirus
 
Quote:
Originally Posted by Pierre (Post 36031760)
I find the whole thing very civilised. I appreciate it may vary depending where you are and whilst the weather is good.

But I happily queue for about 5-10mins to get into my local Tesco or CoOp and it’s all very chilled and relaxed.
You did note that was a reply to "lots of rain", right ?

---------- Post added at 23:44 ---------- Previous post was at 23:13 ----------

In other news, a 106 year old has recovered.

https://www.bbc.co.uk/news/uk-englan...ngham-52296196


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