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TheDaddy 20-12-2020 16:18

Re: Coronavirus
 
Quote:

Originally Posted by Paul (Post 36062993)
Exactly how does it transmit more easily ?

Spike protein according to the egg head on the radio yesterday, it's the way viruses hijack cells and apparently it's easier for the mutant. Tbh I'm just a simple guy, very simple some would say but isn't this the logical advancement, a virus that is easier to transmit but less deadly to the host?

Mr K 20-12-2020 16:22

Re: Coronavirus
 
Bad news for anyone planning to run abroad, we're not wanted.
Quote:

Countries across Europe have started banning Britons from travelling in a bid to halt the spread of the new variation of coronavirus.

The Netherlands was the first to do so, prohibiting those from the UK flying in, followed by Belgium, whose restrictions apply not only to planes but also those entering by car or train (including the Eurostar). Austria and the Czech Republic are the latest nations to take action, and Ireland, Germany and France are also considering which measures to implement.

Italy’s foreign minister Luigi Di Maio announced on Twitter: “As a government we have a duty to protect Italians, so for this reason, after warning the British government… we are about to sign the order to suspend flights with Great Britain.”

Outside of Europe, Israel has announced that anyone travelling from the UK must quarantine for two weeks in a designated hotel.
https://www.telegraph.co.uk/news/202...holiday-plans/

Carth 20-12-2020 16:23

Re: Coronavirus
 
Quote:

Originally Posted by Paul (Post 36062993)
Exactly how does it transmit more easily ?

Very good question.

Somebody may be along soon to explain that a multitude of virologists, scientists and Government busybodies have found - after very extensive testing and data manipulation - that there are 0.0371% more of the virus in droplets expelled from the mouth when shouting in anger at next doors cat wandering through your flower beds.

heero_yuy 20-12-2020 16:28

Re: Coronavirus
 
Quote:

Originally Posted by Carth (Post 36062999)
shouting in anger at next doors cat wandering through your flower beds.

Nerf gun. ;)

Hugh 20-12-2020 16:34

Re: Coronavirus
 
Quote:

Originally Posted by Sephiroth (Post 36062984)
So is it migrants arriving in Kent?

If you mean the variant, there is no evidence of that, no matter how many times the Telegraph tries to dog-whistle that message... ;)

Chris 20-12-2020 16:38

Re: Coronavirus
 
Quote:

Originally Posted by TheDaddy (Post 36062997)
Spike protein according to the egg head on the radio yesterday, it's the way viruses hijack cells and apparently it's easier for the mutant. Tbh I'm just a simple guy, very simple some would say but isn't this the logical advancement, a virus that is easier to transmit but less deadly to the host?

The spike protein is the virus' skeleton key - it 'unlocks' the target cell so the virus can get inside. Once inside it can set about turning the cell into a virus factory. The new variant virus has a more efficient design of spike protein that is more effective at unlocking target cells in the human body.

In a sense the most evolved virus would happily reside in a host body without damaging it or worse, killing it, but as a virus damages a host in the very act of turning host cells into virus factories in reality what it really needs is to be highly contagious, but not rapidly fatal. As long as it can spread to as many other people as possible without killing its host or incapacitating the host so the host doesn't come into contact with other potential hosts, the virus could be said to be doing very well.

Hugh 20-12-2020 16:44

Re: Coronavirus
 
Quote:

Originally Posted by Paul (Post 36062993)
Exactly how does it transmit more easily ?

https://virological.org/t/preliminar...-mutations/563

Quote:

Mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2.

The spike deletion 69-70del has been described in the context of evasion to the human immune response but has also occurred a number of times in association with other RBD changes.
It binds to our receptors better, and avoids the immune response better.

Evolution in action

Pierre 20-12-2020 16:44

Re: Coronavirus
 
Quote:

Originally Posted by Mr K (Post 36062998)
Bad news for anyone planning to run abroad, we're not wanted.

https://www.telegraph.co.uk/news/202...holiday-plans/

Well it didn’t bloody well parachute in did it? We are an island. If the new variant is here, the chances are it’s already in many other places.

Hugh 20-12-2020 16:45

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36063006)
Well it didn’t bloody well parachute in did it? We are an island. If the new variant is here, the chances are it’s already in many other places.

Mutations happen in situ, they don’t have to come from anywhere else.

The same mutation has been found in Denmark and Australia.

Pierre 20-12-2020 16:47

Re: Coronavirus
 
Quote:

Originally Posted by Hugh (Post 36063007)
Mutations happen in situ, they don’t have to come from anywhere else.

The same mutation has been found in Denmark and Australia.

Well done, you have both disagreed and agreed with me simultaneously!

Mad Max 20-12-2020 17:02

Re: Coronavirus
 
Quote:

Originally Posted by Mr K (Post 36062998)
Bad news for anyone planning to run abroad, we're not wanted.

https://www.telegraph.co.uk/news/202...holiday-plans/

So Danish people aren't wanted either then?

Mr K 20-12-2020 17:13

Re: Coronavirus
 
Quote:

Originally Posted by Mad Max (Post 36063011)
So Danish people aren't wanted either then?

You'll have to ask the countries concerned Max old chap.

We seem to have more cases and are more of an issue.

Hugh 20-12-2020 17:21

Re: Coronavirus
 
Quote:

Originally Posted by Pierre (Post 36063008)
Well done, you have both disagreed and agreed with me simultaneously!

Apologies, I mis-read your post.

Damien 20-12-2020 18:27

Re: Coronavirus
 
Well looks like the world is cutting us off!

papa smurf 20-12-2020 18:33

Re: Coronavirus
 
Quote:

Originally Posted by Damien (Post 36063028)
Well looks like the world is cutting us off!

Bloody foreigners:)


as long as the north pole don't cut us off before Christmas we'll be ok.


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